Cadasil

Does anyone out there have Cadasil or know about this disease? Please let me know.

[Dr Rajgopal]

Hi,
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare inherited adult onset disease characterised most commonly by cerebral ischaemic events and dementia. It is caused by mutations in the Notch3 gene with most clustering in exons 3 and 4. CADASIL is an acronym that describes a very debilitating disease characterized by multiple strokes, progressive cognitive difficulties and migraines. In these patients multiple strokes, which begin in early adulthood, accumulate over time leading to early dementia. In many cases sufferers of CADASIL will have migraines for several years before their brains are first affected by stroke.Hope this helps you. Take care and regards !

[Carla46501]

Thanks for the info, I was wondering do you know anybody who has Cadasil