Cymbalta Question

[msloa]

I do not know where to go with my question.  I seem to have exhausted all possiblitites at this time.  I have been on cymbalta for 3 or 4 years now.  However, have been on disability for a little over a year from dizziness (imbalance) and migraines.  It has been confirmed I have constant silent migraines due to mild chairi and cervical disk compression and cervical degeneration.  My question is if I miss one dose of the cymbalta within a day I have the brain bashing migraine and the severe dizziness as bad as when it first occurred.  Plus the fibro pain returns.  Is this withdrawal from the drug or has the drug actually been keeping these things in check for me all this time and I would have been worse off sooner if I didn't start taking it to begin with (for anixety and quit smoking).  Any help is greatly appreciated.

[g2pankhursts]

Unfortunately smoking does affects the amount of duloxetine in your system and blood stream meaning that you will loose between 40 - 50% of the duloxetine dose you take. It is not uncommon for people to have their duloxetine prescription increased if they smoke. Unfortunately it is not uncommon if you miss a dose to be experiencing these problems if your on a high dose, my patients even at a dose of 30mg do experience brain zaps, nausea and vomiting even with just one day missed even more so if you suffer with fibro pain, This is why duloxetine should be withdrawn extremely slowly and only under professional help