Most of us here are not doctors or pharmacists so we don't have the knowledge or the authority to answer that question.
I am not a doctor or a pharmacists, so I can't answer your question. What I can tell you though is that Propanolol is a Beta Blocker used for the preventative treatment of migraine headaches and that Fioricet is a butalbital that is sometimes used for the acute treatment of migraine headache. Fioricet also has acetaminophen and caffeine in it too, as well as the main butalbital medication; and because it has acetaminophen and caffeine in it, it is not an appropriate medication to take daily or multiple times a week for the acute treatment of migraine headache because it will likely cause rebound headache if taken often, although taking it a few times a month is fine. I take a beta blocker but I do not take propanolol so I really couldn't tell you about drug interactions. With the beta blocker I take, I think this combination would be fine, but different beta blockers may have different interactions. I would check with your pharmacist. You could also read the patient information that came with the two medications to check for listed interactions.
If you don't know the answer, don't respond. People aren't looking for your dumb **** suggestion to ask a pharmacist. They already know and are waiting for their appointment to do that. They're here looking for what to expect. If you don't know, don't answer just to hear yourself talk.
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