Anyone famliar with Ganglioside Antibody tests?

Originally posted at the bottom of my first thread, asking folks for insight into my brain MRI. Reposting as a separate topic since it's an independent question. I'd be really really grateful for info anyone has!

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hi everyone!

I have my neuro appointment next Monday, but I just got a blood test result that I was wondering if anyone was familiar with Ganglioside GM1/GD1a/Gd1b/Gq1b Antibody, IgG/IgM?

My GM1 and GQ1b results were normal, but my GD1a and GD1b results were definitely in the positive range (not weak positive or high positive, but the regular positive category listed by the lab). The paperwork I received says "GM2 and GD1a antibodies have been associated with Guillan-Barre variants, motor neuropathies and sensory demyelinating neuropathy, while GD1b has been associated with sensory neuropathy."

The test was ordered by my hematologist who said he wanted to make sure that my MGUS (monoclonal gammopathy of undetermined significance) was not causing any nerve damage. I haven't heard from him yet -- a nurse in the infusion center gave me the printout of the test results a little while ago.

When I see the word demyelinating, I of course think of MS. Does this test have any significance for an MS work up?

Thanks so much!!

--SM

[sllowe]

Hi there,

I'm so sorry that I don't know much about this.  Figured I would bump this up for you - the 1st page is flying by...

[SickMomma_PDX]

Thanks for the bump!

I guess I'm not surprised that most folks don't have much to say about those tests. I guess it's a pretty rare test, and when I called my internist for an explanation of the really scientific stuff I found online, she said she had no clue and would have to do some research and get back to me! :)

I might just have to be patient and see what the neuro says about it on Monday!

Thanks again!

--SM