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333672 tn?1273792789

CCSVI journal update

I was asked for an update and I have posted a short one at http://www.medhelp.org/user_journals/show/165980

To see the past entries: http://www.medhelp.org/user_journals/list/333672

sho
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333672 tn?1273792789
I think you're getting confused with CSF pressure which I think they are at least supposed to measure when doing an LP. Apparently, using newer techniques they can measure the CSF flow using MRI. The whole article is at

http://www.fondazionehilarescere.org/pdf/VHISS-CSF.pdf

sho
Helpful - 0
572651 tn?1530999357
sho,
does this mean these people all had LP's to measure their csf flow?  I'm too tired to read the article for myself tonight :-)

thanks for adding to the conversation.
Lu
Helpful - 0
333672 tn?1273792789
Just wanted to pass on a couple other things that might be of interest to people following this topic.

Zamboni and some of the researchers from Buffalo have an article on the results of their small joint study:

The severity of chronic cerebrospinal venous insufficiency in patients with multiple sclerosis is related to altered cerebrospinal fluid dynamics.

Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular picture that shows a strong association with multiple sclerosis (MS). The aim of this study was to investigate the relationship between a Doppler cerebral venous hemodynamic insufficiency severity score (VHISS) and cerebrospinal fluid (CSF) flow dynamics in 16 patients presenting with CCSVI and relapsing-remitting MS (CCSVI-MS) and in eight healthy controls (HCs). The two groups (patients and controls) were evaluated using validated echo-Doppler and advanced 3T-MRI CSF flow measures. Compared with the HCs, the CCSVI-MS patients showed a significantly lower net CSF flow (p=0.027) which was highly associated with the VHISS (r=0.8280, r2=0.6855; p=0.0001). This study demonstrates that venous outflow disturbances in the form of CCSVI significantly impact on CSF pathophysiology in patients with MS.

http://www.ncbi.nlm.nih.gov/pubmed/20018140

Also, there's an interesting thread on TIMS about a patient who had significant blockages in the jugulars on MRV, but then the radiologist could find no abnormal blood flow or blockages on the CT venogram (which is considered the most reliable test, but is invasive). If nothing else, it shows how many questions still remain about how to accurately image CCSVI problems.

http://www. .com/ftopict-10465.html

Add thisisms to the gap.

sho
Helpful - 0
572651 tn?1530999357
thanks for the update.  I hope you get over this cold and feel better soon.

L
Helpful - 0
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