While on the phone with my sister yesterday, she asked about my health and what's next, etc. She asked me if I was taking something for high cholesterol. (I am) She said that when she tried it, per Dr.s orders, her legs started hurting and cramping, felt tired, etc. and stopped immediately. All her symptoms cleared up! I decided to research this and found some research (albiet biased in some sites) articles about the side effects of statin drugs. There were many testimonials by people who experienced terrible things due to the statin drugs. Well! Virtually all my symptoms can be explained by this. One doctor advises stopping for 2 weeks - claims there should be a noticeable difference withing 10 days - then take the drug again to see if symptoms worsen. There was one article that said the benefits of statin drugs remain for years after stopping! So here goes...I stopped as of last night.
Hugs to all,
Does the onset of your symptoms coincide with the time you began the drug? If so, it could very well explain the symptoms. How exciting!
I would recommend that if you aren't going to call your doc, being the weekend and all, that you at least call your pharmacist to see if it's all right to just stop taking this drug. SOme drugs must be tapered down. Please let your doctor know on Monday that you've stopped taking it in the hopes of alleviating your symptoms.
There were several cases of a muscle disease brought on by some statin drugs used to reduce cholesterol. Quix, do you know the name of the muscle disease??
Many patients on statin drugs complain of muscle aches and leg pain while on these drugs. They don't go on to develop the muscle disease but just have chronic muslce aches and pains.
My mother was one of these patients. She stopped the statin drugs and then all of her leg pain went away.,
Zilla is right. Did your symptoms onset coincide with starting statin drugs?? Also, statins are not known to cause numbness, spasms, loss of motor function in the legs etc. What exactly are your symptoms??
My symptoms in detail are in my journal, but my main trouble is neuropathy in hands and feet and fatugue. I am lucky in that pain isn't my main problem. I have had several tests: MRI of neck and lumbar, GTT, B12, folate, anemia, EMG. The GTT revealed a pre-diabetic condition, EMG shows nerve damage to feet, but no nerve damage to hands. The most affected limb is my left hand. Its function is compromised.. So, next will be an MRI to the brain.
I did find information about statin drugs causing fatigue, neuropathy, brain fog, etc. I googled "major side effects of statin drugs" and " Neuropathy and statin drugs" and tried to find the ones that weren't selling anything. There was enough research and testimonial info to convince me to try the 2 week break from my cholesterol medication. The numbness in my hands came on so gradually, I can't be sure if it coincides with my taking the drug. My feet have been numb much longer, so there is probably damage from my running high blood sugar for awhile without knowing it. My neuro seems determined to find the cause for all. I am grateful for that.
Thanks so much for caring and sharing your knowledge,
The detrimental effects of statins are actually pretty well documented. There is a group of scientists and physicians at the University of California San Diego collecting information on the statins. Elaine is correct about the most severe muscle effects of statins, that is wholesale destruction of muscle tissue and is called rhabdomyolysis, literally "disolving of the muscles." My mom had this after being on one of the early statins, Baychol, which was withdrawn from the market for this very reason.
Contrary to all of the Big Pharm ads, 80 to 90% of all the circulating cholesterol in your body is what you have made yourself. It is NOT from your diet. The liver synthesizes cholesterol via a complex pathway that is used by many other substances in the body. Statins work by interrupting that synthesis pathway, so you don't make cholesterol. However, that pathway is also used for the body to synthesize Co-Enzyme Q-10. This is a substance required for basic metabolism in virtually every tissue in the body. It is in especially high concentrations in muscle, heart and nerves. The body's store of Co-Q10 drops dramatically when the person takes a statin. Animal studies show that if Co-Q10 levels drop too much it will be fatal.
The drug companies recognized this relationship as early as the 90's. One of them actually patented a combo med using a statin and Co-Q10, but never released it. Notice that they all warn against the side effect (and newer ads have stopped calling it "rare.") of muscle pain, because this can be a sign of muscle damage.
I insist that every member of my family who is on a statin take supplemental Co-Q10. Several (testimonial here) had deep muscle pain resolve. Do I believe in the connection? The biochemical pathway is the same between cholesterol and Co-Q-10 and that is exactly where the statins exert their effect. Statins lower tisuue levels of Co-Q10 documented in good studies. The class of drugs are known to have as a "not rare" side effect muscle pain and, as a rare consequence, massive muscle breakdown. It is scientific fact and not a matter of "my belief." Are there other tissues that can be affected by statins?? Absolutely since Co-Q10 is seen through out the body and is necessary for normal cellular metabolism.
Co-Q10 naturally diminishes with age and the elderly are more likely to be on statins. I take a Co-Q10 supp and am not on a statin. I would not take one for cholesterol, and would think two or three times about taking one for MS. Several studies have shown a reduction in number of lesions when taking a statin. But, then so have Prozac and Minocycline. I'd much rather take one of those.
Wow...I have been on a soapbox. Sorry. I'll go find that scientific site about statin side effects.
Here is that site. They are looking for people's experience (testimonials) which can be helpful in determining the nature of future studies. This group also has done controlled studies. This is one of the best uses of testimonial information.
Here is another page from that same site discussing adverse side effects. It might be interesting to read their take also on the role of statins (Yes, there is one) in cardiovasuclar disease. I find this whole site to be fascinating.
Amazing isn't it? Did you find the part about neuropathy? If I can bring my hand back by just stopping this drug, Yippee! In any event, I will not take it anymore. I'm getting some CoQ10 immediately! Vitamin Research Products makes a cocktail for cholesterol that includes CoQ10 I think. I get things from them all the time because they research life extension. I will keep you posted. My fatigue was pretty bad today, but it was really hot and humid. Spent most of the day in front of a fan.
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