Hey, LA! Welcome back. I seem to remember trying low-dose naltrexone for a while, but it really didn't do anything special.
Vitamin D supplements are a great thing - I recommend those. I originally took Copaxone, which I eventually developed an allergy toward. I switched to Betaseron, which caused a blood clot. Right now I don't take anything, as I'm pregnant - estrogen is the best DMD there is.
You might talk to your neurologist about estrogen. The problem with it is that it encourages your blood to clot, so you might have to be on some anti-clotting medication like warfarin. I have to take heparin twice a day.
Hi LA -
Quix, our resident MD, is on sort of a forum hiiatus. SHe checks in very occaisionaly. I just didn't want you to think she was ignoring you :-)
As to DMDs, I can't speak to LDN. My initial DX was SPSM, so I skipped the CRAB's and went right to Tysabri. I had no ill effects from it but it stopped working. I switched to Rituxan (rituximab). Far fewer infusions, usually every 6, 9 or 12 months. I've had 2 so far and they were 9 mopnths apart.
I've had no issues with it. But I supposer that even if you did, winding up in the ER every 9-12 mon ths is better than every month :-)
Kyle