Aa
A
A
Close
Avatar universal
How Long does it take for Baclofen to start working?
Hello everyone.
I took my first does of Bqclofen last night.  My legs started burning.
I don't know if that had to do with the drug or my funky symptoms.
Either way, this mornng i am still having spasms and was wondering how long it usually takes for it to start working and what is the "usual" does who have a lot of speciosity.

I know it's a tough question because we are all different but I figured we are generally in the same boat.
I am going to take 10mg every night for five days and if it doesn't work, I will take 20mg at night for five days.
If that doesnt work, I will take 20mg at night and 10mg in the am.  If that does not work then i am f@&$&@&d!
Sorry for the swear in cognito.

I see the doc on July 11th anyway.
Thanks again, all you kings and queens of ms land!

Kerri
Cancel
6 Answers
Page 1 of 1
1453990 tn?1329235026
As I posted the other day, it typically starts working within 60 min of ingestion and has a serum half life of 6 hours.  My doctor felt there was no need to titrated up over a week.  He had me try 10 mg  at bedtime and if that didn't work, move to 20 mg the next night.  

There is a difference if you are using Baclofen 3 times a day or as needed.  Since I use it as needed, the serum level doesn't ramp up like someone dosing every 8 hours.

Talk with you doctor, because there a few different dosing options with Baclofen.

Bob
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
739070 tn?1338607002
Hi Kerri,

Below is a link to my favorite drug information site. They usually give you  a "normal" dosing schedule but please read this as information only and only act upon what your physician tells you.

http://www.rxlist.com/kemstro-drug.htm

Hope this helps,
Ren
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
572651 tn?1333939396
My neuro had me titrate the dosage - I am now taking 60-80 mg a day (20mg, 3-4 times as I feel it is needed).  

That is a great link from Ren for understanding this drug.  

I hope you find a good balance and it begins to work for you.
best. Lulu
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
338416 tn?1420049302
I found that I could 'feel' the one pill.  After a week, I started to have spasms again, so went up to two pills, and so on.  I stopped titrating when I reached a dosage that would control my spasms.  I still have mid-day spasms, but not all the time, so I take a flexaril when needed.

So yes, you're doing exactly right - keep titrating up until you reach a dosage that controls your symptoms.  I would see if a Flexaril will help in the meantime.

If you're experiencing burning, is that from the spasms?  Or is that a paresthesia?
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
I have tremors caused from a headinjury. the doc, put me on 10 mg of baclofen  and it worked alittle, they are little round pills. so he put me on 20mg but wants me too take 2 of the 10 mg till I run out of the meds and then take 20 mg of which are ob long. anyway, the two 10mg works wonderful. the tremors almost stop. and when i take the 20 mg it seems not too work at all!! what should I do? I thought that if the pharmacist gave me the 20 mg round pills that would work. should I ask him too give me the round one. or ask my dr. for another pill or what?  I am in desperate need. the treamors are just as bad as they were before I started taking them.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
Hi. You have commented on an old post - so it may not be seen. Try going back to the main forum page and chose the Post a Question - if you use your original title for your post jensequitur is sure to see it.

Good luck to you.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Your Answer
Avatar universal
Answer
Do you know how to answer? Tap here to leave your answer...
Answer
Answer
Post Answer
A
A
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Multiple Sclerosis Community Resources