Hi, I am hoping that someone can give me some information on my MRi with and without contrast. In June of this year I had an MRI and I just had another one yesterday and I am a little confused by the results. In June the MRI read:
Findings: Sagittal T1-weighted images demonstrates the corpus callosum, brainstem and cerebellum to be intact. No abnormality increased signal indentified to suggest hemorrhage.
The diffusion: weighted images demonstrate no evidence of acute ischemia. On the flair images, minimal nonspecific 3mm regions of increased signal in the frontal subcortical white matter. No abnormal increased signal identified in the immediate periventricular regions, brainstem or pons to suggest a demyelinating process at this time.
Axial T-2 weighted images demonstrate normal flow-voids in the internal carotid arteries and basilar artery.
Mild ethmoid and right maxillary sinus focal mucosal thickening.
Impression: No evidence of acute ischemia, mass effect, or abnormal intracranial enhancement.
Tiny non specific 3mm regions of increased signal on the flair images in the frontal lobe subcortical white matter bilaterally. These are nonspecific –possibly from prior remote trauma. No lesions in typical periventricular or brainstem locations are identified to suggest a demyelinating process at this time.
Repeat MRI
The repeat MRI was compared to the previous one and the findings were:
The sulci, cisterns and ventricles remain normal. There is no extra-axial fluid collection or intracranial hemorrhage. No mass, mass effect or midline shift. No restricted diffusion or sign of acute ischemic change.
Nodularity callososeptal interface again noted. Corpus callosum again demonstrates normal thickness. Multiple foci of nonenhancing T2weighted and flair hyperintensity again noted within the centrum semivale, periventricular and subcortical white matter. There is no significant interval change within the foci of signal abnormality. No new foci are noted. These foci of signal abnormality enhancement again, these foci of signal abnormality concerning for demyelination such as multiple sclerosis.
There is no abnormal enhancement. The cerebellopontine angles remain normal. The intracranial vascular flow-voids remain normal. Overall stable exam.
Impression: Stable exam. No acute intracranial disease.
Stable multiple foci of nonenhancing T2 weighted and flair hyperintensity again noted within supratentorial white matter. Nodularity callososeptal interface. Again these findings are concerning for demyelination, such as multiple sclerosis.
I would really appreciate any information that someone can give me. I am confused as to why demyelination is a concern now if there were no changes. Also, could one of the MRI’s been incorrect? If I am reading this correctly the first MRI states that white matter is only found in subcortical not periventricular and now it is saying multiple foci noted within centrum semiovale, periventricular, and subcortical but no significant changes.
Over the last several years the only problems that I had were fatigue and problems with my stomach, which did not show anything on the colonoscopy and the stomach issues would come and go. The fatigue it has never went away and continues to get worse. Then this year things began to get worse, the fatigue, tremors in my hands constantly, swelling in the lower part of my legs when running or on long walks occasional dizziness. In September, I started having trouble breathing and that happens on a weekly basis now, it may last a couple of days or just one day. The dizzy spells have become a problem now. One week I may have 3 different spells when sitting or standing and then the next week it will happen every time I stand or sit and my feet have been going numb pretty frequently and it will last anywhere from 10 minutes to an hour. It feels like pins poking me and right arm has been tingling in one particular spot.
With all of these issues that I have had over the last couple of months, then shouldn’t there be more abnormal changes to the MRI if it is really MS? I have had extensive blood work done multiple times and it always come back fine.