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620048 tn?1358021835
Immune Sytem Question...
I keep getting sick and people keep telling me it is my weakened immune system, I really don't know what to tell them, i thought we didnt have weakened immune system ...

Can some explain our immune system to me again?      

hugs, meg    

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1453990 tn?1329235026
If you think about it, MS is not about a weakened immune system, but a more "hyper responsive immune system."  Most immune diseases like MS or SLE, the body's immune system attacks the body.  This is not like HIV where the CD4 cell count is too low to respond.  In MS patients, the cells respond very well.  You have a very healthy immune system.  Maybe a little confused, but not weak at all.

Do you really want to know about all the CD cell types, T cells, B Cells, NK Cells (Natural Killer)?  The point is in MS the immune system is strong, just confused.  The immune system is confused and thinks it is supposed to attack myelin on the nerves in the CNS like it is a foreign invader.  The problem here is we kind of need that myelin and the strength of our immune systems is what does the damage.  

Bob
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1453990 tn?1329235026
Sorry Meg, I really didn't check to see if your DXed with MS before I wrote that.

Opps
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Thanks Bob!! I too have been confused about this. So, is it a bad idea then to take vitamins or supplements that boost the immune system?

Thanks!!!
Kristi
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1453990 tn?1329235026
I was reading a paper about the use of B12 to boost the repair of nerves.  Turns out if your b12 is low, it helps.  Also turns out it your B12 is normal it doesn't.  Normal vitamins or additional doses if you are low in something is most likely a good idea, ask your Dr about it.  Over doing it is not.  Some fat soluble (A and K) come to mind can be toxic or cause clotting issues.  The water soluble ones will just end up being flushed out in your urine.

Bob
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620048 tn?1358021835
Thanks Bob, thats what I thought but can never explain it.  I do wonder why I get sick so much though.

And yes, i am DX'd..

hugs, meg
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620048 tn?1358021835
What did you mean by this...

The problem here is we kind of need that myelin and the strength of our immune systems is what does the damage  /

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1453990 tn?1329235026
The MS immune systems see Myelin on the nerves in the CNS and thinks that myelin looks like another organism, maybe the herpes virus.  So the immune system watch dogs call out other cells that are designed to kill and destroy herpes, but the destroy myelin instead.  This is a very simplified model.
  
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1453990 tn?1329235026
Depending on the drugs you are taking,  they can knock down your immunity.  For example, IVSM is used as an immunomodulator.  Solumedrol turns down your immune system.  
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620048 tn?1358021835
Thanks Bob, my mind gets worse i think, takes me longer to understand.

hugs meg
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620048 tn?1358021835
Okay, my brain has finally caught up, processing is slow...so I get it now !!!

meg
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1140169 tn?1370188676
Are you taking a DMD?

Bob mentioned some drugs will knock down your immune system, and I think the DMD's are in this category.

I've been using Rebif for 3 1/2 months and have caught 1 cold during a trip to the hospital for tests (i think that's where I caught it).

Mike
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620048 tn?1358021835
Hi Mike,

I am on copaxone, not sure about it...

meg
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572651 tn?1333939396
Hi Meg,
Copaxone does not affect our immune system.  That is one of the reasons I  picked it as my drug of choice.


feel better, Lulu
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my doctor explained immune system dysfunction as your body is too busy responding and attacking the wrong things, so that when a real threat comes (ie flu virus) it is not able to respond well to that threat as it's already exhausted its resources fighting wrong things.
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620048 tn?1358021835
Thanks, Lu

This stuff is almost all too much for me to understand now but i keep trying...

meg
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