Rendean's questions about her urogynecologist's statements made me realize that we need a good explanation of the very complicated way in which we control urination. So, this is a condensed description of the process and then in a later installment, a description of my current experiences with Bladder Physical Therapy.
URINATION IN A NUTSHELL
(Disclaimer - the actual act of urinating in a nutshell is NOT recommended. Experience shows that this results in a large cleanup and the uttering of bad words.)
The brain is the master controller of the process of micturition - known in the medically uppity world as urination. The bladder is supposed to be submissive to the power of the brain.
The cycle of urination begins with the bladder filling up. This is passive as the bladder quietly receives the urine produced by the kidneys. The great bladder wall muscle, the Detrusor - has a low tone and allows the filling and stretching of the bladder to hold a normal amount of urine. At the same time the external sphincter keeps a high tone squeezing the urethra closed. As long as the tone in the sphincter is higher than that of the bladder wall, the detrusor, you are continent. (Other continents are Europe, Africa, North and South America, Australia, etc.)
When the bladder is appropriately full the stretch receptor of the detrusor muscle sends a signal to the pons. The pons is part of the brainstem and houses the Pontine Micturition Center, the PMC. The PMC is a major coordinator of all the things that need to happen to stay continent. (see above) Think of the PMC as a set of relay switches. The PMC relays the signal of bladder fullness to the brain, specifically to the Micturition Control Center in the frontal lobe of the brain. The purpose of this center is to cause you and me to be aware of the need to urinate. The brain at the same time sends screaming signals to the bladder, via the PMC, to "hold on" and wait until we find a socially acceptable time and place to relieve ourselves. This is where we recognize that a nutshell, a theater seat or the dance floor is not "the right place." This part of the cycle is completely under the control of the normal person. (Meanwhile I am headed toward the nearest bathroom at a discouraging slow, lurching place looking longing at all nutshells, purses and planters and 'woe be' if I am hurrying through a department store's cookware section!)
As infants the nervous system is immature, and the PMC does not communicate with the brain. So the cycle of filling is followed immediately and involuntarily by emptying. The brain's recongnition of the signal of fullness from the PMC shows up typically by the age of 3 to 5 years and allows successful toilet training.
Upon arriving at said socially acceptable place and removing the necessary layers of clothes, the brain then sends out the "voluntary" signal to let it all out. This signal goes to the pontine center which sends out signals for the urinary sphincter to relax and for the detrusor muscle to contract and expel the urine. This is to happen easily and full emptying to occur forthwith. A relieved *sigh* is optional. Necessary layers are then reassembled and the cycle begins again. (and again....and again....)
This is one of my favorite overview articles on the neurogenic bladder. It is extremely long so I am writing an abreviated version.
Quote: "Neurogenic bladder is a term applied to a malfunctioning urinary bladder due to neurologic dysfuntion or insult...Symptoms of neurogenic bladder range from detrusor (bladder muscle) underactivity (low tone) or overactivity (high pressures), depending on the site of neurologic injury....
MS and the Urinary Bladder
MS is most likely to affect the smooth process of urination by damage to the brainstem or the spinal cord, but a lesion anywhere along the route from the bladder to the sacral nerves to the spinal cord to the PMC to the brain will disturb the whole cycle. With a spinal cord lesion the person will experience a spastic bladder most typically. This is called Detrusor Hyperrflexia or DH. Spastic bladders have high resting pressures. They have "urge incontinence" because the high pressure in the bladder exceeds the pressure in the sphinctor as the sapsm of the bledder becomes worse. This is when the bladder empties too quickly and too frequently with the brain not being allowed to play its rightful role. We may feel an overwhelming need to urinate and begin to look favorably on our briefcase, purse or an innocent nutshell. But, in MS it is also common to have spasms in the sphincter as well. If both the bladder and the sphincter spasm at the same time we won't be able to empty the bladder effectively because the sphincter is tight also. The net result may be retention of urine - a common endpoint in persons with MS. This loss of coordination between the bladder and the sphincter is called Detrusor-Sphincter Dyssynergia, DSD. The normal synergy of bladder contraction coupled with sphincter relaxation is lost.
Some people may assume that severe urinary retention is always caused by a bladder that cannot contract, a floopy bladder, but in MS this is not usually the case.
This article states that between 50% and 90% (depending on the studies) of people with MS who have urinary problems will have Detrusor Hyperreflexia (high tone in the bladder). The typical location of MS damage is in the posterior and lateral columns of the spinal cord. There is a poor correlation between symptoms and what is actually happening. As my urogynecologist stated, "The MS bladder is a poor historian." Along with the findings of excessive pressures in the detrusor muscle, about 50% will also have the discoordination with relaxation of the sphincter. This is called Detrusor Sphincter Dyssynergia - Detrusor Hyperreflexia or DSD-DH
Now, among people with MS who have urinating troubles (beyond the errant desire to pee into nutshells) 20% to 30% will have an areflexic bladder ("a-" meaning "without"). This is called Detrusor Areflexia or floppy bladder. The sphincter my be normal, spastic or open.
First, love the comedic bits! :) Talking about bladder issues is a bit embarrassing...keeping it light and funny helps those of us who are a bit shy... :)
Here is a question (okay maybe one really long one): Which type would cause leakage, and also problems with flow? I experience problems with flow - I will go, but then it will just stop and If I wait a while it will flow again...my trips to the bathroom can take 5 minutes or more...I have also had episodes of cramping...
Dang...I got a message from rendean last night asking about bladder something and completely spaced answering it. Not that I could have anyway...we did pediatric urol and mostly hypospadias and reflux-type stuff.
Thank you for the delightful explanation. I appreciate the full explanation as well the answers from yesterday.
My issues are similar to yours but I do not have leakage. Take that back , afte 3 kids, I do have stress incontinence if I laugh too hard with a full bladder and don't realize my bladder is full.
The leakage I experience is always upon standing - after I am done urinating...I thought the first few times that it happened that I hadn't cleaned up well enough...but it continues to happen - so not sure what is going on.
I know that having kids and also just getting older can cause problems with leakage, but I am only 37 and don't have any kids...so again not sure if this is an age thing or not.
Planning on asking my new PCP on March 28th about it for sure.
Love the comedy and explanation thanks. Has anyone really tried the nutshell to determine if bad words are said?:) Ok, I really did not want to tell my neuro this so I am very glad it came up as I am not diagnosed. I have the same problem as goofysmom, I think I am done stand up only to wish there were a nutshell that caught the rest. Should I purchase a nutshell? Is this the type of leakage we are talking about? I sat there long enough but no we finish the job standing, and I am not male so it is not pretty. :)
I guess I have to tell my neuro huh? He is very serious I don't think I will bring up the nutshell.
Thanks for such a great explanation and the question,
Funny, that happened just the other day! I finished the paperwork, stood up and my sphincter and/or bladder said "not so fast!". Usually, it's just a matter of urgency, and my sphincter not waiting for me to get my pants down. Dang!
Quix, thanks for the informative and funny article!
I have gotten up out of bed and it just started...and I couldn't stop it? It has happened a few times..don't know why...I didn't even feel like I had to go that badly? It was strange and don't know why it happened..what is this called?
Was that fun, or what? :o) Thanks, Quix, I thoroughly enjoyed the explanation and the giggles. A friend called when I was reading it; I read her part of it, and I think she laughed so hard she may have been looking around for a nutshell!
I also have the stop and start flow of urine, and some leakage. My awesome urogynecologist did a lot of testing, and couldn't find any reason for any of my probems, though she said that the reasons don't always show up right away in a neurogenic bladder situation.
One of the suggestion she had for the leakage was a possible diverticulum in the urethra (little pocket in the side of the tube that the urine comes out through) that could retain some urine, which is then pushed out when I stand up.
I had a pelvic MRI with contrast, and it didn't show any diverticulum. It was interesting to see in the report " There are several T2 hyperintense lesions withing the lower uterine segment which is likely to represent small nabothian cysts." Those are just a benign incidental finding, but I thought "gee, I've got glowing spots at both ends!" :o)
Kathy, for a friend of mine, her chronic constipation was at the 'bottom' of her slight leakage. This makes sense to me, since if the bowel gets rather impacted it can impinge on the space the bladder normally takes up. Hey, move over! And problems result.
I think it was you who posted the world's best natural constipation remedy, wasn't it? Or called something like that. Bran and prune juice and other things that can be frozen into ice cubes and added to tea or other drinks. I sent my friend the recipe and it has really helped her. Haven't heard any more about the problem since then.
For me, based on my uro report, I seem to have floppy bladder, coupled with a little confusion in the urination headquarters. Either the bladder would contract and the sphincter just sat there, or vice versa. But I've always been really uncoordinated. :-)
I, thankfully don't have leakage problems. For a year of so, I could not relax the sphenctor. (sp?) Now, I feel the urge, hold it, go. BUT soon after, It starts again. As if my bladder is too sensative. Just a little, and I have got to search for the nutshel or pot, or borrow the kids diaper. LOL again, and again, and again. It is really bad when I go to bed.
I am going to discuss some possible scenarios for the different problems (other than with my humor) that people brought up. But, this should NOT stand in place of telling your PCP or neuro about them.
Leaking a small amount everytime you stand up. Tracy and several people complained about this. (And yes, Tracy, this should be mentioned to your PCP and neuro.)
This is usually a mechanical problem, meaning it has to do with the anatomy and not malfunction of the nerves. Something happens to change the situation at the urethra when you stand.
1) Kathy brought up a common one was a small diverticulum (pouch) coming off of the urethra. It fells with urine while you are peeing and then is squeezed when you stand expelling just enough urine to make you mad. Yes, a nutshell would work here. I have taken several large washcloths and cut them into small 4" squares. Then I use these to catch the "after leak" and this solved the problem.
2) Ess is correct that constipation can cause this problem. The stool sitting in the rectal vault shares the same space as the bladder. The pressure from hard stool can cause some urine to not reach the urethra until we stand up. When this is the cause the leakage is intermittent. Sometimes it's a problems and some not. If we are aware of being constipated we can begin to see if that is causing the problem.
Constipation can also cause us to urinate more frequently because the pressure on the bladder doesn't let it hold as much. Or the constipation may prevent some urine from being expelled at all so it just remains in the bladder. This can be a cause of UTIs in all ages. I frequently saw it in girls in my practice.
3) The shape or position of the bladder may allow some urine to not reach the bladder and when we stand up it dumps toward the urethra. The urethra is still in "pee mode" and releases the urine as we stand up. This may result in the release of a little or a lot of urine.
It is not unusual for women with or without MS to have to learn to wiggle around to get all the urine possible out. They may have to lean to the right and left, rock their pelvis back and forth and then stand up and sit back down. If this is sounding a little like a "lap dance" then you have the picture.
Another common problem is Stress Incontinence. This is often due to poor support of the pelvic floor muscles. The bladder may be full or not full enough yet to have signaled the need to find the "socially appropriate place. The act of laughing, coughing, sneezing, jumping, etc causing the pressure in the abdomen to rise. In a perectly normal person there is also a tightening of the pelvic floor muscles when we do these things, along with the tightening of the shpincter. This causes pressure on the bladder as if it were contracting (but its not). The sphincter is weak and the perineal muscle is weak and can't hold the urine back under the increased pressure and we leak. This is a very shortened explanation of stress incontinence.
The more neurological problems:
Chrisy (goofysmom), Kathy complained about the urine flow starting and stopping. The medical term for this is hesitancy. This can be from one of two problems or a combination of the two. The urinary spincter may suddenly spasm closed mid-stream. This will stop the flow. Or the detrusor muscle of the bladder may relax so there is no pressure to allow the urine out. Mostly this is called Detrusor Sphincter Dyssynergia - lack of a proper coordination between the two muscles. The two need to act in synergy. The sphincter must relax at the same time the bladder muscle contracts.
Guita_grrl - It sounds like you had an episode (the "Not so fast!" one) of having the two muscles being out of sync with each other.
Wobbly - Losing it all without any signal is pure incontinence. Somehow the whole "signal to the brain" thing got sidetracked. This MUST be reported to your neurologist. I would tend to blame the Pontine Micturition Center, but it could be a problem in other places in the whole pathway.
Urge Incontinence - This is when the urge hits suddenly and let's you know you need to pee NOW! This may be coupled with frequency. You spend your life acting like someone trying to steal second base, afraid to get your foot away from the bathroom threshhold. The leakage may begin immediately or during the rush to the bathroom. Often it occurs at the arrival at the toilet itself as you frantically try to remove all necessary layers. Or the classic one is that the leakage occurs as you fumble to get your key in the front door.
The typical problem is that the bladder is spasming like crazy, and the spasms are enough to overcome the tightness of the sphincter. There is also likely a part of the problem that involves the sphincter relaxing too early and allowing the leakage. This is a classic case of Overactive Bladder. Opie, you are correct in stating that your bladder is just too sensitive to having a little bit of urine in it.
It is important for people with urge incontinence to get a urinalysis to make sure they don't have a UTI (urinary tract infection). An infection will cause identical symptoms to Overactive Bladder. A person can have a low-grad urine infection without feeling ill or without burning - just enough to keep the bladder in spasm.
Ess has Urinary Retention, the situation that worries the docs the most - a bladder that just retains the urine and does not send proper signs to the brain that it is full. Or if it does, the detrusor muscle is "areflexic" and cannot contract to expell the urine. This may be coupled with a sphincter in spasm. The concern here is that the bladder my overfill and push the urine up the ureters. These are the tubes that drain urine from the kidneys to the bladder. If the urine backs up into the kidneys it will cause kidney damage. It happens more easily in men, but can happen in women also. Ess they have done ultrasounds of your kidneys or an IVP haven't they?
So, this is how malfunctions of the urinary system can cause the different symptoms and problems we have. I will do a new post on what is happening to me in my Continence Physical Therapy.
An undercurrent to this discussion is how embarassed we are to discuss this with our doctors - many of you may remember I out and out lied about not having an incontinence problem the first time I met my neuro. I then had to fess up the truth very soon after.
I hope you can get over the embarassment and talk about this openly. These doctors have heard this before and it doesn't bother them to talk about urination. Just be forewarned that very few of them will deal with this problem and will send you on to a urologist or urogynecologist.
My urogyno has a good saying she learned from her uncle - if you are a hammer you only look for nails. Translation: Her job is to take care of those areas of her specialty and nothing else. The same goes for all our other doctors here.
Thanks again Quix for the delightful, and to eveyrone else who has kept it flowing.
Quix: I like "floppy bladder" better...makes me giggle! :)
Lulu: you are right about not being embarrassed about these things. For me, it is partially being embarrassed but also being a bit intimidated. I just have to remember that like you said, this is what they deal with everyday, so there isn't any reason to be embarrassed.
Thank you Quix!
I went to my old pcp about 6 wks ago. She said that I had blood in my urin, but no bacteria. She gave me some antibiotics anyway. Then a week later I had the iv steroids. I have made an appointment with a new Inturnest, but it is not until May 5th.
I received the report from the uro-gyno I saw. His report states:
EMG: Very high EMG baseline with versatility, limted reactivity. No relaxation noted with void.
URODYNAMIC FINDINGS: Hypersensitive bladder of increased capacity and normal compliance. Detrusor overactivity provoked by rubbing the lower sacrum but not by traditional maneuvers. Patient also with excess fluid intake. No evidence of stress incontinence. Voiding dysfunction with incomplete bladder emptying. No evidence of bladder outlet obstrucion. No evidence of neurogenic bladder.
SUGGESTIONS: Pt. should decrease her fluid intake by a third. If symptoms warrant, consider InterStim sacral neuromodulation.
Ok, from what you wrote, I do have a neurogenic bladder correct? With the increased tone, etc
Well, we know your urologist has a very narrow definition of "neurogenic bladder." It is the classic "floppy" bladder that can't empty. My question to him is, "You have shown that Ren has abnormal fucntioning of her bladder. This would be due to abnormal neuro signals. If this is not neurogenic, what would you call it?"
My answer is that any malfunction of the bladder that is caused by abnormal nerve signals - too weak, too hypertonic, out of sync, whatever - is a neurogenic state. Neurogenic means arrising out of the nerve function. Mine is the most accepted definition.
Your bladder is "spazzing out." It can be caused to contract abnormally with stimulation of the some of the sacral nerves. You have incomplete voiding and thus, as ess says, are at risk for UTIs. So, yes, it is obvious to me that you have a neurogenic problem.
In the end, it doesn't matter what his terminology is, as long as he treats it correctly. the goal here is to achieve full emptying of the bladder. So let's see what his plans are.
Ess - the urologist recommended decreasing her intake by one third.
I guess that this is as good as any place to give my final thoughts on Continence Physical Therapy. I know a lot of you have had your docs suggest it. I suspect that some of you have been hesitant to do it, which is why I wrote my little essays on the experience.
First off, I found that most of my problems were a learned response. I do have neurogenic problems, in that, my sphincter is too hypertonic (it's spasming) and my bladder is secondarily irritated by it. The bladder and the sphincter don't work smoothly together. My problem was urge incontinence. I was totally convinced that the whole problem was neurologic and was offended and embarassed when the PT told me there was a behavioral component.
But, I am doing the program and walkin' the walk. She was right. By, learning to retrain that horrible insistence that I get to the bathroom NOW, most of the problem was solved. I rarely get that insistent scream to run. And I am slowly gaining some undercarriage strength. I do believe that the numbness and weakness I have in the nether regions is mostly neurological, but I am going to get it as strong as I can. I have graduated to a 2/5 strength.
The point that I wanted to make here for you is this: The first problems I had were likely the neuro ones. But, having had an accident - which to me was horrifying and totally a blow to my pride - I began overreacting to my urges to pee. I would rush to the bathroom to prevent the embarassment. I became like Pavlov's dog. The bell would ring and I would react. This became ingrained, and the urges grew all out of proportion. This could happen to anyone. The reinforcer was a strong negative one and it was intermittent - this is the strongest kind of reinforcer if you remember back to Psych 101. My life truly was at the mercy of my tantrumming bladder. What should have been little sensations in the background took center stage and dominated my life.
Now that I have learned to curb my enthusiasm, so to speak, life is truly much better. Not all the way, but leagues ahead of where I was. Somehow I truly did think I was too smart/savvy/well-adjusted - whatever - to let a thing like this happen, but in retrospect, I see how it all makes sense.
It appears to me that the women who go into this PT specialty are those that like and respect women and believe strongly in empowering them. I would encourage any of you for whom this has been suggested to try it. Even if it helps just a little - well, that would be great. At no time did I ever feel embarassed or violated. It was like a friend was teaching me a skill.
I didn't report on it, but the last skill set they have me working on is strengthening some of the core hip muscle groups, like the hip adductors and the abductors. These are the muscles that pull the knees tightly together and the ones that pull them apart (like against a therapy band). Strengthening them has a synergistic strengthening effect for the muscles of the pelvic floor.
There are other parts to the PT that I apparently didn't need or qualify for. There really are little Kegel barbells and there are electrical stimulation techniques.
And that is the end of my seemingly endless essays on Continence Physical Therapy.
I hope it was all entertaining and enlightening and in a nutshell.
Thanks for your earlier responses. I thought I had a neurogenic bladder but the uro (who seemed totally perplexed by the findings) did not. My neuro never labeled it as such but did ask me what the uro told me about my bladder. Neuro's big concern was Ess's comment on UTI's but those have not occurred recently(past year and an half). The uro's big concern was the ability to cause contractions by stroking the sacral area...he kept saying that's just not right...be sure and tell your neuro. I did tell him and he just shrugged his shoulders.
As for not emptying my bladder, on the initial visit before the urodynamics, he did a bladder ultrasound for volume- 48 cc. I had voided about an hour before and felt no urges. He stated that would be a normal level.
Also, what the dingbat uro didn't recall, obviously, is that I take a diurectic along with other hypertensive meds. The too much fluid intake was wrong. It was just the fact that I had not taken the evening dose of diurectic the day before I started the voiding diary; so therefore I had a large output. The purpose of the uro-dynamics was ,in part, to ascertain if the bladder spasms I was having had a connection to the diuretics.
At least he couldn't mess up the computerized readings regarding the EMG portion. He received pure data. His interpretation just seems way off.
Wow this was just the information I've been looking for. Terrific read Quix with your usual added humour. :-)
I have the frequency thing going on & recorded 16 times yesterday with possibly missing some along the way. I have the urge to go & really really have to go with sometimes not quite making it. I have had bladder problems since my 20's when I used to not be able to go at all which meant a trip to the ER to get a catheter inserted. I don't have this problem more recently.
I have had the reoccurring UTI's in the past with retaining after I void but this seems to have improved greatly. I had urodynamics done back in 2007 & I do remember comments such as I didn't have a regular flow & retention but I don't have the report to know anything further.
I feel like my bladder has probably shrunk from all the mixed signals over the years & now I only need to have a little bit of urine to send me off to the bathroom. I have tried many of the things like toe curling to hold on for longer but this is really just increasing my chances of having an accident. I also feel quite uncomfortable & so I have a desire to just go to relieve myself. My flow is still up & down but I've had that for so long it's part of me now.
I actually don't think my problem is totally neurogenic but probably the miss information from my CNS has taken me to a place of problems I may not be able to solve. Anyone heard of bladder stretching lol. I'm not up for anymore medications at this stage but I will probably have further testing once I can get past the wait list at the hospital.
Thanks again for all that information. It's very much appreciated.
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