Hi Cashu -
Glad you brought this up. We've talked about this at length in the past - but not recently.Here is just one discussion I think you and others will enjoy reading....
http://www.medhelp.org/posts/Multiple-Sclerosis/MRIs-and-gadolinium-contrast/show/1096679
-Shell
The sequencing is important to whether the gad is going to light up if the disease is active. You should double check with your neurologist about the protocol that is being followed with your scans. I would hope that all the techs know the MS protocol, but we all know how unreliable that can be.
The question might be what is causing your new symptoms - are they directly related to lesion activity?
It is also possible that the MRI is not picking up all the lesions - we know that everything is not seen on imaging.
I'm sorry to hear you are having these new problems without a clear understanding of why it is happening - it would be greati f we could capture it all in pictures.
be well, Lulu
Thanks to both of you for your responses!
A number of the scans were ordered at the time within days of having new symptoms so I thought that some of the lesions would have enhanced given the timeframe.
I'm going to ask about the order of the sequences following the Gad administration. If the first scan after the Gad is administered is a T2 scan it is still allowing the time to elapse before the T1 images are obtained. If not, I'm going to request that they wait five minutes. I hope that comes across as a reasonable question/request.
Thank you.
Carrie
They should wait a minimum of 5 min before doing the T1 scans post-GAD. Some centers will give you the GAD and then do the last T2 scan (which will take more than 5 min) and then start the T1 post-GAD sequences. Since GAD will only show up on the T1 sequences, this is considered an acceptable procedure and you don't have to wait in the bore doing nothing for 5 min.
Bob
Well, Bob is definately your man for this question. From what little I know, the enhancing has to do with the age of the lesion, not how long the dye has been in your system.
It could be that the timing of the MRI's just happen to be after the lesions have been established and aren't "new" anymore (over 60 days?), hence they don't enhance from the dye.
Hope you get more detailed answer to your question. Good luck.
Julie