Aa
A
A
Close
Avatar universal
MS vs Sjogren's
My primary symptom is memory loss affecting  my ability to function personally and at work. PCP thinks dpression, psychiatric NP does not. MRI shows "multiple periventricular focci of increased T2 FLAIR signal suspect demyelating process possible migranous pallor. Neurologist did LP and EVP and said they were normal except Sjogren's antibodies were high with no explanantion  why and she stated no follow up was necessary, not even repeat MRI in a year. SSA 1.26 SSB 1.66, greater or equal to 50 was positive. ANA less than1.40. I don't not have HTN, migraines, hx of smoking/drinking or any of the other things that can cause white matter changes per my neurologist. Please help me know what might be wrong and what type of MD to see next. I don't know what to do. Thank You, Monica RN BSN
Cancel
8 Answers
Page 1 of 1
338416 tn?1420049302
Your MRI indicates that you still need a workup to eliminate MS as a diagnosis, or Sjogren's.  Is the neurologist your regular doctor, or just somebody you were referred to?  I would seek a second opinion - make sure you have your MRI results, blood tests and films.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
1627868 tn?1333889942
I agree with obtaining a second opinion.  I did just this and each one of them has a completely different opinion.  (Weird, being that they study the same thing in school, lol!)  There are plenty of other tests that could and maybe should be ran.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
572651 tn?1333939396
Many people here went through one, two, three and even more neuros before finding one who could see the big picture.  I would move on for the next opinion.

Your MRI sounds like it needs to be looked at again - the areas mentioned can be prime hot spots for MS.

goog luck, Lulu
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
572651 tn?1333939396
that should be good luck and not goog luck. :-)
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
152264 tn?1280358257
Just to add my voice to the choir--second opinion!! from a different neurologist. If that first one didn't want to do any follow-up with an abnormal MRI, that seems VERY unusual. They should always do at least one follow-up. Memory loss is a serious thing. Have you had neuropsychological testing?

Good luck and keep us posted.

Nancy
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
Thank you everyone very much. Nancy, I probably didn't explain my situation well due to my cognitive difficulties. I had MRI, then LP to "rule out" MS which was "negative" except sky high sjogren's antibodies. Now the neurologist states nothing is wrong. She says there can be other causes for the spots on MRI, but I have NONe of the other potential causes and she can't answer why i have the spots then. I also asked since the spots represent white matter changes, could those changes be causing my memory loss even if not due to MS and she said no.  I will get a second opinion, but will probably have to  pay out of pocket according to my insurance.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
I can't figure out how to post on the Dr forum, can you help me?
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
152264 tn?1280358257
Monica, it sounds like your neurologist is not serving you well at all. You deserve an explanation for memory loss and for the Sjogren's antibodies. I know neurologists can't explain everything, but it sounds like she's given up too easily and is not dealing with your issues.

I don't think the doctor's MS forum is taking questions anymore, and hasn't for a long time (as far as I know).
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Your Answer
Avatar universal
Answer
Know how to answer? Tap here to leave your answer...
Answer
Submit Answer
A
A
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Multiple Sclerosis Community Resources
RSS Expert Activity
233488 tn?1310696703
Blank
Marathon Running Done Over Many Yea...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
233488 tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
748543 tn?1463449675
Blank
TMJ/TMJ The Connection Between Teet...
01/15 by Hamidreza Nassery , DMD, FICOI, FAGD, FICCMOBlank
Top Neurology Answerers
667078 tn?1316004535
Blank
Durham, NC
198419 tn?1360245956
Blank
572651 tn?1333939396
Blank
Dayton, OH
Avatar universal
Blank
751951 tn?1406636463
Blank
Caledonia, OH
Avatar universal
Blank