Not all spots are Demyelinating Plaques caused by MS
Many people come to our forum because they are told they have "white spots, or lesions on their brain, and the doctor will not dx them with MS, thought they feel they have met the Criteria by their own research or what they have learned here.
We’ve discussed at length why MS is so difficult to dx, the mimics, and how not all lesions are created equal, or by the same disease process.
We state that there are other causes of brain lesions, or white spots, discuss the differential diagnoses and provide resources. I hope this list further helps to bring about awareness of why the doctor may not dx you with MS. And, this info is in our health pages too - so for newcomers who have not had the opportunity, please browse through them.
Injuries can cause brain lesion, immune disorders, diseases, viruses and I’ve even read that some exposure to certain chemicals can cause brain spots, or changes. Sometimes the doctor simply cannot identify the cause.
Here are just a few (and, I'd like to add to this - so those w/differential dx w/lesions or spots - please list your dx) We'll compare this list to the health page, and add if it's missing:
I always like to look at the Radiology Assistant. It has some great examples of MS lesions, sarcoidosis lesions, lesions caused by ischemia, and more. It's what I looked at when I was trying to read my own MRIs (not recommended!)
In my case Multiple Myeloma - (bone marrow / blood cancer)
I should qualify this though and say Myeloma is rare, and in my age group (mid 30's) really rare! MS seemed like a much better explanation (my symptoms were systemic and include both signs such as irregular reflexes and symptoms such as fatigue) But the one issue was no MRI spots (well when reading the MRI later there was evidence of Myeloma but it was missed since it is bone spinal lesions, not spinal cord lesions.
Seems we have many limbolanders, and some who are mention they are uncertain of their diagnosis.
Please know there are many causes of lesions - this list is compiled from the above mentions - and, there are more.
I cannot stress enough that not all lesions are caused by MS, or even a disease process.
Chronic white matter disease:
commonly associated with diabetes, high cholesterol, atherosclerosis, and high blood pressure.
sarcoidosis lesions, lesions caused by ischemia
glioma or brain tumor
Multiple Myeloma - (bone marrow / blood cancer) I should qualify this though and say Myeloma is rare (Sumerlvr)
Be sure to visit the link in this discussion:
There are also 36 major red flags that point to non-MS dx (in the link in the above discussion), 11 minor red flags that suggest possible dx and 32 clinical paraclinical and lab and imaging findings/examples.
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