Hi, Brin, Welcome to the forum! Are you diagnosed? Or dealing with paresthesias for an unknown reason.
The hypersensitivity to touch is called allodynia. It can be a real problem as it can interfere with clothing and intimacy.
I don't have the problem, but I have dealt with it in other contexts.
Yes, some people find that certain fabrics are better than others. Some here have reported that soft fabrics like flannel or microfleece are better. Have you tried flannel lined slacks? If you have MS the downside could be the warmth.
In medical practice I found that sometimes it was the "movement" of the fabric on the skin that caused the problem. I found that sometimes wearing a firmer fitting undergarment could relieve the intolerable burning or pain. The undergarment fits to the skin and does not move so much.
Examples could be silk or Cuddleduds longjohns.
Also, have you spoken to a neurologist about trying to treat the paresthesias?
We have three good Health Pages on paresthesias and treating them. You might read
http://www.medhelp.org/health_pages/Multiple%20Sclerosis/Paresthesias---Things-That-Go-BUZZ-in-the-Night/show/378?cid=36
http://www.medhelp.org/health_pages/Multiple%20Sclerosis/Nerve-Neuropathic-Pain---A-Primer/show/371?cid=36
http://www.medhelp.org/health_pages/Multiple%20Sclerosis/General-Principles-of-Treating-Neuropathic-Nerve-Pain/show/452?cid=36
If you do go on treatment or if you have had a problem with meds please be sure to read the third one written by a pain management doc for us.
I hope others will drop by and add their experiences. So....skirts or mu-mu's are out, huh?
Welcome again,
Quix