What is . . .

[nette573]

I recently had lab work done  and I was wondering what  LEIDAN FACTOR V is?  Can anyone tell me?  

I will go on tuesday to have a stress test done.

Then my husband and I will go to Houston to see grandson get baptised.  It is a loooong trip for us.  I am kinda worried it is the first trip since my episode.  It takes us about 8 to 9 hours to drive.

Please say a prayer for us that we get there safely!  My husband is 13 years older than me and I usually have to drive too.

Lynette

[sllowe]

Hi there,

JUST FOLLOWING UP ON OUR DISCUSSION WITH THESE FACTORS.  THIS IS WHAT MY LABS SAID PRIOR TO MY DX.

Lupus Anticoagulant Reflex (again, this is not a lupus test, just a bad ol name that has never been changes)

PTT-LA  83.9  (flagged)
PTT-LA Mix 80.1  (flagged)
Hexagonal Phase Phospholipid 5.3 (within limits)
Drvvt 33.1 (within limits)

Interpretation Comment (from the lab):
No lupus anticoagulant was detected.  Results are consistent with the presence of one or more factor-specific inhibitors.  Since the dRVVT was within normal limits, the factors in question are VIII, IX, XI, XII and the contact factors

TO ALL:
The reason I'm posting this information is because Nette brought this up, and it's something that I have always feel strongly about.  While researching the mimics of MS, one of them is Hughes Syndrome (APS), or sticky blood syndrome.  I was beating my head against a wall with these Drs trying to get to the bottom of what the results of this test meant.  

They did not have any answers for me, nor were they concerned.  Maybe there is no need for concern, however, part of me feels that major, major testing needs to be done for those being worked up for MS, to rule out APS, and do do this, I understand that anti-cardiolipin, and anti-phospholipid tests and others have to be run, extensively.

IF ANYONE HAS INFORMATION TO ADD TO THIS THREAD, IT PLEASE DO SO, IT WOULD BE GREATLY APPRECIATED.

BE WELL,
SL
P.S. nice to see you Siddy, and Nette, hope you had a safe trip

[Siddy1]

Hey Quix

Yes, I know... long time no post.  I was trying to concentrate on walking but it ain't working!!!   As always I read (and sometimes weep) at the posts on this Forum.  Everyone is so supportive and I hope each and every one of you reach and exceed my age (68). .

Love to you all.

Marcie

[Quixotic1]

Siddy, Hi, I'm so glad you were lurking!!  I was going to jump in and tell them about you.  Please stay a while and tell us how you're doing or Private message me.

So, Everyone, what she said.

Yes, SL do let us know what was flagged and what was recommended.  These things are not to be dismissed without a looksee.

I have the opposite problem.  I have Teflon platelets.  Bleed too easily

Q

[nette573]

Thanks yall for the comment.  I really have no clue when it comes to labs just a few I know.  You  were a big help to me.  I will say a prayer for yall too.

Lynette

[sllowe]

Hi Nette,

I'm glad you brough this up.  I had some weird flags from my bloodwork early on prior to my MS dx, that stated I should have the V, IV, and X and some others tested.

It was a  note from the lab, due to Lupus LA, and Mix Anti-coagulant test, it's not the one for lupus, it's just gien a bad name.  He said that he did not know why they ran it, but I really didn't care, just that it suggested further testing. I don't have all the info in front of me right now, but I'd sure be interested to know more about these "factors" myself. Especially where clotting is concerned.

My Neuro did not know what they meant, and said to go to a hemotologist.  My MD was clueless, and did not run labs for the ones they suggested.  I did not pursue it, since there were so many other things going on. But, with what I have going on right now, which is some sort of reaction, that includes a lot of swelling, and the appearance of my skin, I wonder if it's indirectly related.

I will say a prayer for you, and you push for those tests.  I'll get my paperwork and see exactly what it said, reference those factors, and re-post w/more info.  I did do some research on those factors, and it can get hairy to interpret yourself, but please push for someone who can interpret those tests to you, and don't let themm disregard them, just because they are looking at other things and it's not their field.

be well on your trip,
SL

[Siddy1]

I developed a  blood clot (DVT) 5 years ago in my left leg behind the knee. I got the reason a  few years later.  The results from lab tests performed for  the diagnosis of MS showed that among other things  I had inherited one copy of the  V-Leiden gene.  None of my other family members have ever had a clot so I presume inactivity had something to do with it. Still, it is good to know because I am aware of it and take Plavix daily.
I am not surprised that the left leg was affected because that is the weak one.

[nette573]

Thank you!  I kept trying to find it through web md. Wow, I sure do appreciate it.
Lynette

[Nerve_Wrecked]

This is what I could find about Leiden Factor V:

Factor V Leiden thrombophilia is an inherited disorder of blood clotting. Factor V Leiden is the name of a specific mutation that results in thrombophilia, or an increased tendency to form abnormal blood clots in blood vessels. People who have the factor V Leiden mutation are at somewhat higher than average risk for a type of clot that forms in veins, such as the deep veins of the legs (deep venous thrombosis), or a clot that travels through the bloodstream and lodges in the lungs (pulmonary embolism). Most people with the factor V Leiden mutation never develop abnormal blood clots, however.


I'll keep you in my thoughts during your upcoming journey. I pray it will be safe, and enjoyable!

Christine