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ms lessions

How many lesions are necessary to diagnosis ms?
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1453990 tn?1329231426
In my case, I had One MRI lesion and One clinical lesion (Optic Neuritis - pointing to demyelination of CN2 without MRI evidence) and then I developed 4 more MRI lesions and an additional clinical lesion (Trigeminal Neuralgia - pointing to demyelination of CN5 without MRI evidence.)   Two exacerbations separated by more than 30 day in two different areas (ON was cerebral and TN is midbrain) demonstrates dissemination in space and dissemination in time.

Some doctors are comfortable with this type of diagnosis, while others are (shall we say) more difficult.

Bob
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Avatar universal
Just curious,,, would that mean like, hyperreflexia, optic nerve damage, one sided tremor in hand, and overshooting or undershooting a target. Are those, Clinical lesions?

Thanks, pam
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1045086 tn?1332126422
Bob will probably be back to clarify but I think by "clinical lesion" he means clinical evidence (visible to the doctor during an exam) that a lesion exists even though it doesn't show up on the MRI.

Mary
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1637739 tn?1371688706
I am no expert, but if I remember correctly, it's the location and  the "time" and "space" requirement.  Atleast one old and one new lesion shown on MRI along with history showing more than one flare.  
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352007 tn?1372857881
What's the difference between "clinical lesions" and "MRI lesions"?
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1453990 tn?1329231426
Well, you need two "clinical lesions" and no MRI lesions (hyperintensities) for a diagnosis of MS.  One clinical lesion and one MRI lesion would be CIS.   Most of the time, it usually doesn't work out that way.  

Bob
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1394601 tn?1328032308
Justt one is enough!
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900662 tn?1469390305
Hi,  

its not just number of lesions,  it's location, location . location  and size and shape.


Visit our health pages  and this link may be helpful
http://www.sciencedaily.com/releases/2011/03/110309162117.htm

take care

Johnniebear
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