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non tipical ABO antibities possible MS test?
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non tipical ABO antibities possible MS test?

I was diagnosed with MS in 2003.  I had been ignoring strange symptoms for several years prior.  

About 5 years before I ever had an MS symptom I had tried to donate plasma for some extra cash.  If any of you have ever donated plasma you will remember that the process for being accepted as a donor is quite lengthy.  

They actually throw away your first donation after they send it in to be tested for things like hepititis (hepatitis), aids, drug abuse, and tryglycerete levels.  I didn't have any of these so I made it till the third donation before I was called into the Doctors office and told that they would not be able to use my plasma and please feel free to have a free cookie or something.

I was told that my plasma showed that I had non ABO antibodies.  I asked what that meant.  The doctor told me that it just meant that I had been sick at some time, probably when I was little, and that when I got better my antibodies had changed.  That they still worked but that they were different than everyone elses and since they were different they could not give my non typical plasma to someone with typical antibodies.  

I have been thinking about this alot now for several years.  I wrote Montel Williams a letter about this subject right after I was diagnosed, but I fear it was not clear enough..  I couldn't find anything about the subject then and I have no medical background so I don't know what else to look at.  Today when you put the words " non typical abo antibodies multiple sclerosis" into google it brings up 18,300 results.  From skimming these it seems that several people are looking into this as a possible cure.  

I am thinking of it as a possible diagnosing tool however.  I was 23 when I tried to donate plasma.  I was 29 when I got my MS diagnosis.  Every doctor that I have ever talked to about MS has told me that the best possibility for MS right now is the ABC drugs.  That it is not a cure but that it slows the progression of the disease by up to 40% thereby slowing the inevitable disability of the disease.

Could a simple blood test give patients a head start on slowing the progression??

The plasma clinic where I donated blood gave this test to everyone who could possibly be a potential donor.  It couldn't really be that expensive to administer... I know that a months worth of Rebif costs me 1162 dollars a month and it is just a rake in the pathway of the disease.  If I had started taking an ABC drug back in my plasma donating days would I still be working??

Anyone know where else I could go with this thought?

Thanks in advance

Amish Erin!

  
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5 Comments Post a Comment
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195469_tn?1388326488
bumping up this post for others to make sure they see and maybe have some comments.Sorry this post got pushed all the way to the bottom of the page Erin.  Hopefuly our members may have some comments on this.  I know nothing about these anti-bodies and if they have anything to do with MS.

I'm sorry.

Heather
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307874_tn?1242759398
bump up for ya.
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147426_tn?1317269232
I don't know anything about using "Atypical" antibodies for a possible diagnosis.  I looked it up and couldn't find anything.  Could you give me a link to what you were reading?

Atypical ABO antibodies - also called isoantibodies - are actually fairly common in people.  It would likely depend on the exact isoantibody in question.

Quix, MD
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432312_tn?1265648574
Multiple sclerosis (MS) patients (332) and controls (305) selected from Caucasian populations in the New York City area and in Tucson, Arizona, were tested for ABO blood group factors A and B, and Rh factors C, D, E, c, and e. [1980]  
Our results demonstrate that the MS patients differ from the normal subjects with regard to the Rh, ABO and Lewis erythrocytic antigens. [1991]


This is one of the first paragraphs in this article...

http://www.ihop-net.org/UniPub/iHOP/gs/86171.html

The google search has changed now and I can't find the same articles.  The other day there were 1800 articles with this search inquiry but today there are...Results 1 - 10 of about 2,070 for non typical abo antibodies multiple sclerosis. (0.42 seconds)"  maybe I ought to just wait a week and google it again

I heart google

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Avatar_f_tn
Hi my name is jesica and on4/12/2008 diogosed with it too, and i have not been able to find anything like to cure it or anything and my doctor said thast iam just on of the lucky ones to have it- he said..... but i was wondering if there anything that we can do togeter so that other pepole could have there voices heard because its really unfair that people have it and cant donate in today's world!!!!!!!!!!!!!!


I just really think that it unfair because people have this and there's no informantion about it or anything that we can do to reverse it it are system but maybe drug up on pills or opr types of drugs that have nopt even been out that long and not get no where in life woth them or maybe just make us more sick or make us die in fact, so these really nothing that we can do unless they really take action on it because it has enffect on are bodies and are future!!!!!!!!!!

     Thanks Jessica Brown
                  ( Columbus, Ohio)
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