I am about 6 weeks and 2 days pregnant. Muscular dystrophy runs in my fathers side of the family. My two aunts my uncle and grandmother all past from this disease. My father brother and I have never been tested for it but we show no signs of having it. My dad is 53 and still showing no signs. Is there ANY possibility that my baby could inherit this disease? Or am I just being paranoid?
I found this:
"These conditions are inherited, and the different muscular dystrophies follow various inheritance patterns. The best-known type, Duchenne muscular dystrophy(DMD), is inherited in an X-linked pattern, meaning that the mutated gene that causes the disorder is located on the X chromosome, one of the two sex chromosomes, and is thus considered sex-linked. In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition. In females (who have two X chromosomes), a mutation must generally be present in both copies of the gene to cause the disorder (relatively rare exceptions, manifesting carriers, do occur due to dosage compensation X-inactivation. Males are therefore affected."
So, my thought is that if it is passed down on your father's side, then your father must not be a carrier or he would have the disease himself. If he does not have it, he can not pass it to you on your X Chromosone and therefore you can't pass it to your child, regarless of his/her sex. This is assuming your dad does not show signs because he doesn't have the condition. Perhaps he should (and you should!) be tested to be certain.
Copyright 1994-2016 MedHelp International. All rights reserved.
MedHelp is a division of Aptus Health.
This site complies with the HONcode standard for trustworthy health information.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.