I have been having chronic irritability for a while, I am not sure if it is this psychoactive herb called kratom that is causing it, depression or both. Because I had chronic irritability in the past before I discovered the kratom. I cant stop obsessing over it, the irritability is so unbearable its like I want to crawl out of my skin. My psychiatrist tried to put me on a anti-psychotic but I am afraid to take it. She never diagnosed me with anything specific, she just said "mood disorder" I also have severe anxiety and depersonalization all the time, that is why I take the kratom, I guess it is kind of addictive. I don't know what to do? I am back on a low dose SSRI. What is going on in the brain to make someone chronically irritable in simple scientific terms?