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Aspergers and PVL--need expert help
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Aspergers and PVL--need expert help

Specific Question:  
Is there a neurologist, neurosurgeon, or radiologist who can explain what is found on the MRI of a child with Asperger syndrome that is similar/same/or coincides to any periventricular leukomalacia-PVL findings?  

History:  
A child with PVL diagnosed via MRI at around age 4 tends to be very well-functioning and not have the problems associated with PVL, or the severe disabilities that coincide with it.  Child is now 10 and exhibits traits, very strong traits of Asperger syndrome.  

Child was initially taken to (a now retired) pediatric neurologist at age 4 (when the diagnosis of PVL was made) because parents suspected autism (as did teachers at preschool) due to autistic-like behaviors.  

DX of PVL was made by solid findings on MRI and maternal history of kidney stones with kidney infection from 7-9 mos gestation (total of 9 stones passed in last 2 mos of pregnancy).  Child was born full-term, "code blue" with initial suspected need for transfusion (because of cord asphyxiation), however, deemed not necessary by neonatologist when child's APGAR/vitals increased steadily.  Child reached normal milestones with only slight/very minor disability for first and second year, parents noticed some "behavioral" episodes.  Parents noticed odd behavior by about age 3 and began questioning it with no results.          

Of Note:  
This child now has a positive (low) ANA, increased TSH with no other thyroid abnormalities, increased creatinine, and is suspicious for JRA.  Recent IQ testing done by the local school placed child in High to Superior range of functioning.

Any ideas?  Thank you.  
Related Discussions
Avatar n tn
Did you ever receive an answer? We have a VERY similar son. He was premie (33w5d) due to maternal pancreatitus (pancreatitis)/HELLP (he is also a twin).
PVL was dx after a mild seizure at 18mo. His delays were mild (@/< 10%) for the 1st 2 years but some questionable behaviors. The older he got the more "odd behavioral issues". Real questions came up before K. He received numersous dx from Dyspraxia, Sensory, ADHD etc and finally was dx Aspergers on 8th bday (after parents suspected it 2+ years). His TSH test like your sons, his iron is low ... lots of odd things but to my knowledge no ANA testing?
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