I have a nine yr old daughter with many unexplained problems going on. Her med history is ground glass infiltrates on lung CT, lung biopsy showing eosinophilic pneumonia, eosinophilia of 14%, chronic sinusitis requiring 2 surgeries in past 18 months,ANA 1:320 speckled,GI problems requiring Nisson and gallbladder removal,bleeding ulcers, biopsies of colon showing mild chronic inflamation
(inflammation), gallbladder shows same thing, sinus biopsy showed increased eosinophils and chronic inflamation
(inflammation). Now the sural
nerveNerve biopsy
Nerve conduction velocity biopsy they did shows "axonopathy, active and chronic, mild", her neuroologist didn't know what to make of it becasuse he thought it would be
normalNormal saline flush because even though she has symptoms(tingling and occasional
numbnessNumbness and tingling) he found no
muscularBecker's muscular dystrophy
Duchenne muscular dystrophy
Muscular dystrophy
Muscular dystrophy - resources weaknessWeakness, or loss of sensation on exam. So he called a
nerveNerve biopsy
Nerve conduction velocity expert at the university and was told it could possibly be normal, that he thought a normal person could have mild axonopathy, but also said it could be mild neuropathy. So they have advised a nerve condution study to determine. My question is , is what they are saying true? Can you have pathology showing mild axonopathy that is actively and has chronically degenerating the axons and it be normal, especially in light of everything else going on? She fits the critera of Churg-Strauss, a vasculitis. Although there has only been questionable evidence of vasculitis on her lung biopsy and not in any of the other biopsy sites, including the nerve. Can you have a Churg-Strauss neuropathy with out eosinophils or vasculitis in the biopsy? Thanks for your input!