B12 link with M S?

Is there a link between B12 deficiency and multiple sclerosis? I have been diagnosed with both and think there has to be.

[Stilicho]

Hello

There isn`t any study ,which can construct a link between Vit.B 12 deficiency and Multiple sclerosis.
The genesis of MS is a big problem for all research teams,so it lies in darkness.We don``t know ,whether it is an infectious trigger,nor a problem in the genetics.
Vit. B 12 deficiency is a very often diagnosis. A lot of people ,who have problems with alcohol, have a converted gastric mucosa.The function of normal gastric mucosa is to secerne a pre - vitamin B12 - so called " intrinsic factor ". This binded the "Extrinsic factor ", coming from your food. Later in the small bowel the resorption of this complex starts.
There are a lot of other reasons for Vitamin B12 and Folic acid deficiency,but there is no correlation to Multiple Sclerosis.

With best regards

Stilicho

[Dr Sharma]

Hi there. There has not been any clinical studies to substantiate this association. Vitamin B12 deficiency is associated with peripheral neuropathy, which causes tingling, and numbness, overlapping symptoms of multiple sclerosis. Multiple sclerosis is a chronic demyelinating neurological disorder where the disease phase is characterized by active phase and remissions. It has multiple symptoms and signs and is a diagnosis of exclusion. The symptoms of multiple sclerosis are loss of balance, muscle spasms, numbness in any area, problems with walking and coordination, tremors in one or more arms and legs. Bowel and bladder symptoms include frequency of micturition, urine leakage, eye symptoms like double vision uncontrollable rapid eye movements, facial pain, painful muscle spasms, tingling, burning in arms or legs, depression, dizziness, hearing loss, fatigue etc. You have many of these symptoms. The treatment is essentially limited to symptomatic therapy so the course of action would not change much whether MS has been diagnosed or not. Apart from clinical neurological examination, MRI shows MS as paler areas of demyelination, two different episodes of demyelination separated by one month in at least two different brain locations. Spinal tap is done and CSF electrophoresis reveals oligoclonal bands suggestive of immune activity, which is suggestive but not diagnostic of MS. Demyelinating neurons, transmit nerve signals slower than non-demyelinated ones and can be detected with EP tests. These are visual evoked potentials, brain stem auditory evoked response, and somatosensory evoked potential. Slower nerve responses in any one of these is not confirmatory of MS but can be used to complement diagnosis along with a neurological examination, medical history and an MRI and a spinal tap. Take care.

[Stilicho]

Hello

Thank you for your very exactly description of multiple sclerosis.I only want to say ,that there is no association in any study has been shown.Anyway i thank you for these complete informations.
With best regards
Stilicho

P.S. : Please excuse my poor english.I am a GP from Germany ,who is working and living in Liechtenstein.