NEUROLOGY EXPERT FORUM
CAVERNOUS ANGIOMA STATISTICS

CAVERNOUS ANGIOMA STATISTICS


  News articles regarding the coroners report following the recent death of Florence Joyner included a statistical reference to cavernous angioma which I would be interested to verify. According to one article I read, 25% of the population has such a lesion, although not all cases are detected, and not all lead to activity such as seizures.
  Further, having been recently diagnosed with cavernous angioma, I am interested in learning if any statistics have been collected regarding "average" sizes of such lesions. If such, I would be pleased to learn such information.
  Thanks very much for your assistance!  
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I have attached two references below which may be of interest if you have
access to a medical library.
The incidence of CEREBRAL cavernous angiomas is between 0.4 and 0.7 %
the incidence is the rest of the body is higher but I do not have data
outside the nervous system.
One study reported that seizures was the most common single presenting
problem occurring in 23%.
One recent paper reported an range in size from 1.0 t0 3.0 cm with and
average size of 1.6 cm
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Kattapong VJ.  Hart BL.  Davis LE.
Department of Neurology, University of New Mexico School of Medicine, Albuquerque.
Familial cerebral cavernous angiomas: clinical and radiologic studies.
Neurology.  45(3 Pt 1):492-7, 1995 Mar
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Zabramski JM.  Wascher TM.  Spetzler RF.  Johnson B.  Golfinos J.  Drayer BP.  Brown B.  Rigamonti D.  Brown G.
Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital, Phoenix, Arizona.
The natural history of familial cavernous malformations: results of an ongoing study.
Journal of Neurosurgery.  80(3):422-32, 1994 Mar.




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