NEUROLOGY EXPERT FORUM
Can CIPD occur with Conduction Block at the Head of the Fibula?

Can CIPD occur with Conduction Block at the Head of the Fibula?

  I have had painful burning/tingling that began in June in my right foot/leg and now involves most of my body (including tongue, face, etc) most of the time.  In August, I developed a bilateral footdrop, which was shown by EMG to be peroneal palsies at the fibula head (partial conduction block).  The footdrop improved from August to October, but then relapsed and I developed proximal weakness in both legs and hyporeflexia in the left ankle.  This problem resolved by mid November.  I continue to fall over with eyes closed but can appreciate light touch at all sites.
  Relevant laboratory studies (dibetes, liver function, CK, CBC, metabolic panel, ANA, B12, folate, RPR, serum immunofixation, lyme titer, chest film, MRI of brain)have all been negative.
  I was recently evaluated at a highly-regarded center for peripheral neurology.  A new EMG confirmed the previus block at the fibula head and also found a (new)"mild ulnar neuropathy at the elbow."  The neurologist concluded that the fibula head & elbow neuropathies were likely due to "habits" (i.e., crossing my knees, etc.), although both I and people who have known me for years believe that I am not a "knee-crosser." The paresthesias were thought to be due to some as yet unknown, but unrelated cause.  I was told that my problem can not be CIPD becuase "the criteria exclude conduction block at the head of the fibula."
  It seem highly improbable to me that I would simultaneously develop 2 rare and unrelated peripheral neuropathies.  My questions are (1)does CIPD ever occur with conduction block at the head of the fibula? (2)Do you have any suggestions regarding other possible cause for my problems?
  Thank you so very much.      
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Dear Barbara,
thanks for your question,
Let me first say that peroneal and ulnar neuropathy are not that uncommon, at least not at our center. The criteria for CIDP does not include conduction block and so the answer to your first question  is yes, provided other criteria for diagnosis including electrodiagnostic studies are supportive of the dx.  Your problem did sound like conduction block at the fibula head and this is supported by the fact you recovered from it.
There is a condition called Hereditary Neuropathy with Liability to Pressure Palsy (HNPP). This is a hereditary condition in which the patient develops recurrent nerve palsy (it could be ulnar at the elbow today, peroneal at the fibular head on the left next time, followed by the right.) after a trivial pressure (you said you are not habitual leg crosser or elbow leaner...)
THere is also a condition called mononeuritis multiplex, which basically means several neuropathies (different ones, e.g a carpal tunnel on the left, an ulnar neuropathy on the right, a peroneal neuropathy on the right leg, and a femoral neuropathy on the left leg) in one person. This is associated with several conditions, mostly rheumatologic or vasculitic in nature, although some infections such as HIV and Lyme can also produce it.
I hope the above information helps.
Good luck to you, if you live near Cleveland and would like to get another opinion, pse call 1-800-CCF CARE, we have a world class Neuromuscular program here.





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