Corona Radiata Lession

I'm a multiple sclerosis patient (26 years). I was diagnosed on 2004. I'm good right now and taking interferon since 2006. Since 3 years I've been experiencing some hand problems. It's getting worse, and I have raynauds in both of my hands and bilateral edema. I've my hands nerves pinched (carpel tunel, cubital, etc.) Right now it's something that I can handle, but i'm concerned about it. The las MRI showed a lot of lessions that compromised both sides of the corona radiata, a big lession on the mid pons and many others. My question is: It could be possible that the big lession on the corona radiata (bilateral) affects the peripheral nerves of my hands. My neurologist made me cervical MRI and Toraxic MRI and it was ok. The last time he told me to go to the reumathologist because it could be possible to have a connective tissue illness (colagen desease). I have being studyng all about the condition, and I thought that maybe the lession in the corona radiata (nerve fibers) could affect the peripheral nerves of my hand. What do you think about it?...Thank you...

[Christopher R Newey, DO]

Thanks for using the forum. I am happy to address your questions, and my answer will be based on the information you provided here. Please make sure you recognize that this forum is for educational purposes only, and it does not substitute for a formal office visit with a doctor.

Without the ability to examine and obtain a history, I can not tell you what the exact cause of the symptoms is. However I will try to provide you with some useful information.

Lesions in the corona radiata, which is the area of cortical nerve fibers, can cause symptoms in the hand alone. However, this is usually easily determined on examination depending on the specific muscles involved in the hand. Peripheral nerves have a specific pattern of innervation – motor and sensory. It is difficult to say if the cause is an upper motor neuron (i.e., brain/spinal cord) or lower motor neuron (i.e., peripheral nerve) without the ability to examine you. I would suggest you continue following up with your physician. You may wish to speak to him/her about getting an EMG/NCS performed to assist in localizing the nerve and muscles involved.

Thank you for this opportunity to answer your questions, I hope you find the information I have provided useful, good luck.