PANDAS is a controversial diagnosis that has emerged from the medical literature in the last few years. Some physicians do not believe there is really an association between strep
throatCancer - throat or larynx
Throat swab culture infections and neurobehavioral
disordersAdjustment disorder
Anorexia nervosa
Asperger syndrome
Autism
Autoimmune disorders
Bipolar disorder
Bipolar disorder
Bleeding disorders
Borderline personality disorder
Bulimia
Chronic motor tic disorder such as obsessive compulsive disorder or tics, while others have collected several case studies of pediatric patients who appeared to have the disease. According to one study from NY, the patients with PANDAS responded well to antibiotic therapy for the infection and had complete resolution of the behavioral symptoms when the infection cleared. Recurrence of the behavioral symptoms was present in half of the patients, but this was associated with recurrent infection. As for the possibility of Tourette's syndrome, the diagnosis requires both verbal and motor tics for one whole year. It's more common in boys, starts about age 7 (most before age 11), can certainly occur in previously healthy children and has a genetic component (meaning it's inherited in a number of cases). Some reports state that the majority of patients with tourette's have a peak in their tics during adolescence and then the disease slowly peters out as they get older. A small percentage have complete remission after the end of puberty.
Dr. Gerald Erenberg is an outstanding ped neurologist here at the Cleveland CLinic who specializes in tic disorders. If you are interested in making an appointment, I'm sure he would be happy to see your daughter. Good luck.