I've seen some reports that topical application of DMSO gel is effective at relieving the pain of peripheral neuropathy. In a check of the Medline searching under 'pain' and 'DMSO', I found one study that supported this claim. My question is, is DMSO harmful if applied to the skin? Does it leach into the blood stream? I want pain relief but I don't want to endanger my health (DMSO got some bad pr some time back)
Thanks for the question. DSMO is a common vehicle used to transport many drugs. It has many biological effects including antiinflammatory, antioxidant and local anesthetic effects. If it will have a role in treating pain related to PN is not certain. It has been shown in very limited studies to have a role in complex regional pain syndromes. We are not using it here to treat PNs. There are reports to suggest that it can leach into the blood. At CCF we are not using this medication and if you were interested in using it I would only do so as directed by a physician familiar with its use.
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