Depomedrol

Posted By Jim Burke on April 17, 1998 at 13:03:28:







I have an 80 year old female chapter member who suffers from Myasthenia Gravis and osteoarthits of the knees. She is on a daily maintenance of 10mg of Prednisone for the MG. She has occasional injections of 80mg Depomedrol into the knee for the osteo. When she receives these injections, she states that she goes into a 'blue funk', often becoming very lethargic and listless. Her orthopaedist claims this is a withdrawal symptom from the Prednisone. Is it possible that the 2 drugs are interacting?.
Thank you.
J. Burke