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It is a usual practice to test for ammonia every three months. It is usually combined with the therapeutic drug monitoring for Depakote. You may repeat the test just before the appointment with your doctor, so that he has fresh ammonia reports.
The diagnosis of MS is arrived at after clinical history, examination and investigations. Your history does not hint towards MS. The lesions on MRI may not be significant.
Elevated ammonia as a side-effect of divalproex sodium (Depakote) can lead to symptoms such as altered mental status, confusion, and delirium. Some people do present with such symptoms even at low plasma levels.
Ideally, when elevated levels of ammonia is found in the setting of Depakote therapy, close monitoring of plasma levels should be done every week. If the elevation should persist, discontinuation of this drug should be considered.
The interpretation of migraines as the cause of the tiny lesions on MRI are only suggestive and are not absolute. The lesions are probably non-specific and could have been caused by other conditions.
Thank you for your response. I know that as medical professionals, we sometimes read too much or too little into our own health issues. I will call my doctor to discuss the time line in which I need to have my ammonia level rechecked.
Hi there. Thanks for the interest. I take a B12 injection every 2 weeks. Last lab check, it was still zilch. He said that it's due to malabsorption. Said dietary supplement would do no good.
It is a usual practice to test for ammonia every three months. It is usually combined with the therapeutic drug monitoring for Depakote. You may repeat the test just before the appointment with your doctor, so that he has fresh ammonia reports.
The diagnosis of MS is arrived at after clinical history, examination and investigations. Your history does not hint towards MS. The lesions on MRI may not be significant.
Regards
Elevated ammonia as a side-effect of divalproex sodium (Depakote) can lead to symptoms such as altered mental status, confusion, and delirium. Some people do present with such symptoms even at low plasma levels.
Ideally, when elevated levels of ammonia is found in the setting of Depakote therapy, close monitoring of plasma levels should be done every week. If the elevation should persist, discontinuation of this drug should be considered.
The interpretation of migraines as the cause of the tiny lesions on MRI are only suggestive and are not absolute. The lesions are probably non-specific and could have been caused by other conditions.
Hope this answers your query.
Are you taking supplemental magnesium and Omega-3's.
Carol