Can uterine fibroids and/or ovarian cysts cause sciatica-like symptoms? I've had burning/stinging/stabbing pain in both glutes, hamstrings, calves and feet for 6 years. I've tried everything under the sun to get rid of the pain (long-term physical therapy, steroid injections into L4-L5 disc and piriformis muscle, yoga, deep tissue massage, rolfing, acupuncture, etc) but nothing has helped. I just found out that I have 2 golf ball size fibroids on the back of my retroverted uterus, (one on left side, one on right side), plus a large complex cyst on the left ovary. The pain has progressively gotten worse over time and I never have a pain-free day. Sitting is worst, followed by standing and lying flat on my back. Walking/jogging doesn't hurt.