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Neurology  (Expert Forum)
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Glioblastoma Multiforme
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Glioblastoma Multiforme

by peetl, Jul 22, 2003 12:00AM
After my wife was operated on for a Glioblastoma Muliforme, we were
told that they were able to do a complete resection.  Additionlly, that the tumor was in the left peridal lobe.  Much of the information talks about the fact that a complete resection is not achieved that often, I have yet to find any information on what percentage of surgey's the complete rescetion is achieved.  Secondly, does the fact that the tumor was in the peridal lobe rather than the frontal lobe have a effect on surviability.  What effect do the newer treatments, computer guided surgery, 3-d confroma radation with boost have on survival.

by CCF-Neuro-M.D.-CS, Jul 26, 2003 12:00AM
Sorry for the delay. I wanted to check on a few things so I can give you a more precise answer. I will have a complete response within the next few days. Thanks for waiting.
Member Comments (6)

by ccfneuromd, Jul 28, 2003 12:00AM
It is wonderful that they were able to achieve a gross total resection. The fact that this was in the parietal lobe should not impact on survival. However GBM by definition is an invasive tumor, therefore removal of every tumor cell is unlikely. Howevere a gross total resection does increase the median survival. The image guided surgery does assist the surgeon during the resection. Most radiation performed today is 3-D conformal. The most important thing regarding treatment is that you are at a cancer center. It appears that patients treated at a cancer center do better overall then those who are not. I wish you the best of luck.

by BiotechGuy, Jul 29, 2003 12:00AM
TO THE INDIVIDUAL WHO HAS CONCERNS OVER GLIOBLASTOMA MULTIFORME.
There is a Small Biotech Company called PEREGRINE PHARMACEUTICALS out of Tustin California,
[peregrineinc.com AND pphm.net]
BOTH very useful sites for the latest in Cancer Treatments.

Their drug therapies, 'TARGET' tumors directly with conciderable efficacy and very little side effects. Peregrine's Lead drug, COTARA®, has been shown to be very effective in GLIOBLASTOMA MULTIFORME. The well-know Scientist/Oncologist, Dr. Philip Thorpe is the inventor of this new approach to Cancer.
  
    The company has been given PHASE 3/'FAST-TRACK' status by the FDA to commence PIII Trials. (It could be underway)
AND the People's Republic of China, their 'SDA' (State Drug Authority), is about to make a decision to clear the drug for use outright, possilbly this year.
  
The Chinese are claiming amazing results with Cotara, (though a slightly different formulation than Peregrine's version.)
but in all this by the Chinese have been done in collaboration with PEREGRINE PHARMACEUTICALS.

   Check the Peregrine web site for Clinical Trials.

Good luck.

by stady, Aug 27, 2003 12:00AM
my aunt has glioblastoma and the doctor said that she has 6 months without treatment and maybe  a year with it and i wanted to know more about it
thanks
a worried niece

by jlbjamaica, Oct 07, 2003 12:00AM
Hello. I am from Italy. My father in law got surgery on sept 18th, and the result was a Glioblastome multiform, the biggest of them about 1cm, white color. The surgery report says that everything has been removed. it was located on the frontal left side. he is recovering well, and is currently doing exercises to recover the full functionality of his right leg and arm.
Today he was visited by the doctor, Professor Michele Reni from Milan San Raffaele hospital, who prescribed him a first round of 6 weeks (5 per week) of radiotherapy, to start not earlier than one month after surgery. No chemio was discussed this time. Doctors will give my family a % of success only after this first round of therapy.
I am the only one who knows so far how bad this cancer is, by reading litterature on the internet.
My questions are: should chemio be prescribed as well? What are the real chances of success? Patient is 64 years old, and has never had any helath problems in the past.

by jlbjamaica, Oct 07, 2003 12:00AM
Hello. I am from Italy. My father in law got surgery on sept 18th, and the result was a Glioblastome multiform, the biggest of them about 1cm, white color. The surgery report says that everything has been removed. it was located on the frontal left side. he is recovering well, and is currently doing exercises to recover the full functionality of his right leg and arm.
Today he was visited by the doctor, Professor Michele Reni from Milan San Raffaele hospital, who prescribed him a first round of 6 weeks (5 per week) of radiotherapy, to start not earlier than one month after surgery. No chemio was discussed this time. Doctors will give my family a % of success only after this first round of therapy.
I am the only one who knows so far how bad this cancer is, by reading litterature on the internet.
My questions are: should chemio be prescribed as well? What are the real chances of success? Patient is 64 years old, and has never had any helath problems in the past.
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