Horrible Sensations, Burning Pain In Feet, Help!

Hi, My Name Is Joshua Young,

  For about a year I've had burning in my feet, at firstFirst progesterone mc10
First progesterone mc5
First-progesterone vgs 200
First-progesterone vgs 400 it was intermittent, now it's constant.  I also have other strange sensations in my feet and legs, electrical impulses, twitches, pins and needles and VERY painfulPainful menstrual periods burning.  I have a bit of the tingles in the tips of my fingersAmputated finger
Amyloidosis on the fingers
Clubbed fingers
Cryoglobulinemia - of the fingers
Finger pain
Herpes zoster (shingles) on the hand and fingers
Janeway lesion on the finger
Kawasaki's disease, peeling of the fingertips
Nail abnormalities
Replantation of digits
Ringworm, tinea manuum on the finger as well.  

I've been to a neurologist, I've had a Brain MRI, EMG/NCV, SSEP and LOTS of labs.  ALL are normal (excluding high monocytes and bilirubin, was diagnosed with Gregs Disease) I'm 21, male and hypertensiveHypertensive heart disease. I do not smoke or drink alcohol.  My B12 is normal, so is FolateFolate deficiency.  

We can't figure out the problem, I did show that I had Hypothesia in my legs and feet and a few declining reflexes in my hands and arms.  

The pain is unbearable, what could this be?

[Neuro Forum]

Thanks for using the forum. I am happy to address your questions, and my answer will be based on the information you provided here. Please make sure you recognize that this forum is for educational purposes only, and it does not substitute for a formal office visit with your doctor.

Without the ability to examine you and obtain a history, I can not tell you what the exact cause of your symptoms is. However I will try to provide you with some useful information.

There are 2 types of nerves in our body, large and small. The small nerve endings supply the skin and sweat glands. There are two types of sensory neuropathy: small fiber and large fiber (depending on the size of the nerves affected). With small fiber neuropathies, symptoms including burning or buzzing or other vague symptoms starting in the feet and hands then in some cases spreading to other parts of the body. The EMG/nerve conduction studies (NCS) (tests done to check for neuropathy) will not show an abnormality, and a definitive diagnosis can only be made with a skin biopsy so that the number of nerve endings can literally be counted. There are other tests of the function of small nerves that can be ordered, such as QSART testing which looks at how much sweat the skin makes, since sweating is in a sense of function of these small nerves. There are several causes of small fiber neuropathy, including diabetes, vitamin deficiencies, autoimmune problems, protein disorders, HIV, and others. In young males, a disorder called Fabry's disease should be considered for severe burning in the hands in feet in some cases.

If a type of neuropathy is confirmed, treatment for neuropathic pain (pain coming from nerves) includes neurontin and lyrica, and medications such as elavil (which is an antidepressant but has actually been found to be helpful with neuropathic pain as well).

Continued follow-up with your neurologist is recommended; evaluation by a neuromuscular specialist (a neurologist specialized in disorders of the muscles and nerves) may be of benefit to you as well.

Thank you for this opportunity to answer your questions, I hope you find the information I have provided useful, good luck.

[JoshuaY46013]

Hi, My Name Is Joshua Young,

  For about a year I've had burning in my feet, at first it was intermittent, now it's constant.  I also have other strange sensations in my feet and legs, electrical impulses, twitches, pins and needles and VERY painfulPainful menstrual periods burning.  I have a bit of the tingles in the tips of my fingers

I've been to a neurologist, I've had a Brain MRI, EMG/NCV, SSEP and LOTS of labs.  ALL are normal (excluding high monocytes and bilirubin, was diagnosed with Gregs Disease) I'm 21, male and hypertensiveHypertensive heart disease. I do not smoke or drink alcohol.  My B12 is normal, so is FolateFolate deficiency.  

We can't figure out the problem, I did show that I had Hypothesia in my legs and feet and a few declining reflexes in my hands and arms.  

The pain is unbearable, what could this be?

[JoshuaY46013]

I have another question, I got my results back from the MRI
My question is I had to take a SSEP test in my arms and legs, the doctor preforming the test said the results were normal BUT had desensitization in my feet.  

I had a Cervical MRI, the results read :

Slight reversal of cerical lordosis.

C2-C4 disc, canal and neural foramina are unremarkable

C4-C5 Slight Dehydration, minimal broad posterior bulging, central canal and neural foramina are within normal limits.

C5-C7&T1 disc, central canal and neural foramina are unremarkable

SO, if the SSEP test was normal, does that mean that this is not what is causing my problems in my feet and arms.  I had absent reflexes in my hands and my  neuro said there was weakness in the left arm.

Any ideas?