Effexor is well known to cause sweating, sleep disorders (such as insomnia) and anxiety. Of note, it can also cause seizures. Another possibility however is that your blood counts could be abnormal due to the Lamictal which can produce some of your symptoms. Talk to your doctor about these symptoms. It may be helpful to get a routine CBC or blood count just to make sure everything is ok. Otherwise, consider adjusting the dose of effexor or switching to another medication that doesn;t have the potential to cause seizures given your past medical history. GOod luck.