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Nerves in the brain and spinal cord have a covering called the myelin sheath which is important in the propagation of nerve impulses. In demyelinating diseases, this protective covering is damaged, which results in slowing or blocking of nerve signals that control muscle strength and coordination, as well as vision and sensation.
Some examples of demyelinating conditions include multiple sclerosis, optic neuritis, transverse myelitis, acute disseminated encephalomyelitis, etc.
However, MRI findings are not absolute and should always be correlated with clinical symptoms.
Hope this helps.