Muscle aches

  I am a 39 year old active male.I had a stomach virus 7 months ago.Since then i have been in the hospital 5 times.I have had nemerous tests.My Ck level has been from 250 to 500.I have had an Emg neg results.I have had evey gastro test,all neg(they did remove my gallbladder).I have a constant ache in my left ankle,neg findings in the othro.Blood tests for everything.Cbc diff,ana,ua,pt/ptt/rpr/esr/rf/HepABC all neg.Hep antibodies all neg.Motor neuropathy all fine.They did fin elevated copper in my muscle.A liver biopsy _ for wilsons same with copper blood tests.I do have a swollen salivary gland.Doctors say take vitimans.Epstein barr was elevated.On the muscle biopsy25% atrophoic fibers on esterase stain.Sed rate normal,lymph normal.Believe me this is not in my head,the doctors say something is wrong but they can't grasp it.Any ideas thyroid tests also normal.The gland doctor said check for a connective disorder? Would that cause this muscle burning.The best way to describe it is the burn you feel when you work out.Does a muscle biopsy rule out MS and Sle?what do you suggest.
  Thank you for you Time and effort
  Dan Iburg
  I just want to get back to being the dad my kids love.

[CCF neurology MD MM]

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The symptoms you describe are suggestive of a myositis, which is
inflammation of muscles associated with aching pain in the muscles and
increased CK levels. Myositis may follow a viral infection or be just one
manifestation  of a connective tissue disorder.
As with any disease there is a spectrum of involvenmetnt and your problem
may simmply have not deveolped sufficiently to cause clear-cut diagnostic
abnormalities on diagnostic testing.
This is good insofar as it means that the process is low grade and mild
in severity, but frustrating due to lack of a definite diagnosis.
A muscle biopsy would not address the issue of possible MS, although the
symptoms would not suggest this in any case. Neither would it exclude
SLE, which is a possibility worth considering.
I would suggest that if the symptoms do not subside then a repeat of the
antibody tests to exclude SLE / Lupus and other connective tissue
disorders would be a good idea, otherwise this may be ultimately labelled as
probably low grade transient post viral myositis, which should resolve in time.