NEUROLOGY COMMUNITY
Muscle biopsy results

Muscle biopsy results

Hello -

I have been suffering from muscle weakness for about 8 years now.  It has been fairly stable and I have been functioning well with my daily activities until 2 months ago.  The only changes in the last 8 years are that I developed muscle stiffness 2-3 years ago (well controlled with medication), and extreme muscle fatigue, pain and cramping, and difficulty swallowing, which developed 2 months ago.  

I had a muscle biopsy 7 years ago which showed angulated grouped fibers consistent with a neurogenic process.  However, the neurologists have not been able to link this to a specific disease.  Could you please give me some insight into what these results mean?  I have tested negative for SMA, mitochondrial disease, and the MuSK Antibody, but was not tested for AChR.  EMGs are also negative.  

I would appreciate any insight you could provide.  Although the neurologists say that they will eventually figure this out, my quality of life has changed drastically in the last couple of months and I feel like they are missing something.

Thank you.
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Avatar_m_tn
I had a biopsy and have been diagnosed with neuragenic atrophy reinnervation.

Can you tell me what all that means.

Thank you

Andy
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