I'm a fit and healthy 49yo male with tingling and numbness in the feet and toes that started 8 months ago. Twitching in the calf muscles was also noticed about a month later. At that time, I also started getting a burning/prickling feeling in the back of the legs. Went to a neurologist and had a neuro exam plus a full brain/spine MRI, nerve conduction studies in the legs and lots of blood work over a period of a few months. All came back normal except for an elevated blood inflammation marker reading of 20. After 4 months, the neuro said that he couldn't diagnose anything and said not likely to be anything serious like MS or ALS.
More recently I've been getting isolated twitches anywhere on my body. Just a single twitch somewhere and then another one somewhere else about 15-30 minutes later. I just feel these rather than seeing them because I never know where the next one is going to be. On some days they are more frequent and on other days none at all.
The latest worrying thing is two incidents of major intermittent twitching in my left bicep which lasts on and off for about a day and then goes away. The first incident was 6 weeks ago and then another one 2 weeks ago. When the twitching is happening I can stop it by just moving or tensing the muscle.
At the moment, the leg twitching has settled down to fairly constant minor flickering like a bag of worms in various parts of the calves, and the foot/toe tingling/numbness and the leg burning/prickling feelings are also fairly constant. I have no muscle weakness or atrophy. Any ideas?
The normal imaging and nerve conduction tests help to exclude many disorders. There is a condition called benign fasciculation syndrome which causes twitches all over the body at vatious points in time. Also excercise, fatigue, stress, and electrolyte disturbances can cause muscle twitching. Nothing that you have stated clearly points to disorders such as ALS or MS. However, if the symptoms persist, it is reasonable to obtain a second opinion. I would recommend going to an academic center, if you do. Good luck.
Forgot to say that I have no problems with balance, dizziness or eyesight. The neuro said not likely to be anything serious, but my body is acting strangely and I am still very worried about ALS or MS.
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