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Neurology (Expert Forum)
Myasthenia Gravis, recent change in symptoms
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Myasthenia Gravis, recent change in symptoms
by Sheila-Fas, Jun 04, 1997 12:00AM
Re: Myasthenia Gravis, recent change in symptoms
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Posted by CCF Neuro MD on June 11, 1997 at 10:30:23:
In Reply to: Myasthenia Gravis, recent change in symptoms posted by Sheila Fass on June 04, 1997 at 23:55:10:
: Have had MG41 yrs. in gd control since thymectomy in 1959. Take 60 mg. mestinon 2 X day. Recent symptoms close off airway when lying down, like sleep apnea. Increasing dose to 3 X a day eases symptoms, but causes cramping in legs at nite. What's to do? Thank you; Sheila
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Hello Sheila,
The symptoms of having altered breathing patterns with periods of brief cessation of breathing during sleep is one of the main symptom seen in sleep apnea. Just because you have myasthenia gravis does not mean that you can’t have another disease also. It is interesting, however, that you have noticed an improvement with an increase dose of your mestinon. It suggests to me that your MG may play a role in causing these symptoms. Because the complexity of your case I would suggest that you seek a consultation with a neurologist immediately to have this problem resolved. Your neurologist may order a sleep study to help identify the problem if the cause is not immediately clear after his initial evaluation. If it is thought that an increase in your dose of mestinon is needed, then using an extended release dosing of mestinon at night time (called mestinon TS) may help decrease the cramping you are currently experiencing. If you are interested in a second opinion at the Cleveland Clinic Foundation, you may want to get an appointment with Dr Mitsumoto who is a neurologist with a specialization in MG. You can make an appointment by calling 216-444-5559.
This information is provided for general medical education purposes only. Please consult your physician for diagnostic and treatment options of your specific medical condition.
