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Myasthenia Gravis treatment

by shlomoca, Oct 18, 2009 03:08PM
I have Myasthenia Gravis and type 2 diabetes. My doctor has prescribed Cyclosporine. Most people with MG that I have spoken to have been prescribed Celcept.  My creatinine level is elevated to 1.6. What do you feel would be the reason my doctor would keep me on Cyclosporine  instead of switching me to Celcept. The elevation of my creatinine is interfering with my current diabetes treatment.

Thank you
Member Comments (1)

by Rowena Santos, MD, Oct 18, 2009 10:21PM
Hi,
How are you? Myasthenia gravis is a chronic autoimmune neuromuscular disease which presents with varying degrees of weakness of the muscles. This can be controlled with medical therapy such as anticholinesterase agents (neostigmine and pyridostigmine) and immunosuppressive drugs (prednisone, cyclosporine, and azathioprine). Anticholinesterase agents help improve neuromuscular transmission and increase muscle strength while immunosuppressive drugs improve muscle strength by suppressing the production of abnormal antibodies. Treatment depends on the severity of the weakness, which muscles are affected, and the individual's age and other associated medical problems such as diabetes. Talk to your doctor about this to clear any anxiety. Take care and best regards.
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