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Need answers

About two years ago my uncle who is 47 started loosing feeling in his legs now he can barely move them he has had multiple MRI's and a spinal tap with no diagnosis yet he is now on disability as he has lost his ability to walk he has also experienced fainting spells does anyone have any idea what it can be?
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I forgot to mention that his leg function periodically does get a little better at least for a short time
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