First of all, keep in mind that I am unable to diagnose you because I am unable to examine you, this forum is for educational purposes.
The symptoms that you describe sound the most like carpal tunnel syndrome or a possible peripheral nerve entrapment at another site along the arm. Carpal tunnel syndrome is caused by compression of the median nerve at the wrist and classically causes night time wrist/ and even sometimes whole arm numbness/pain. This is thought to be related to repetative stress injury, but also has other factors ivolved such as the size of your canal etc. For this I would suggest that you have an EMG (Nerve-Muscle test) with nerve conduction studies(NCS) to evaluate for signs of carpal tunnel. The first line of treatment is to obtain wrist splints that are worn at night which help by maintaining the wrist in a striaght position. Multiple sclerosis(MS) does not present this way. MS presents with focal numbness, optic neuritis, and/or dizziness/imbalance, etc, that lasts for several weeks then improves. It is not correct that MS does 'not show up on MRI in the early stages'. Most patients with MS have multiple lesions on their first MRI, after presenting with their first symptom (the reason is, that much of the brain does not give rise to symptoms when a lesion is present and only "eloquent" areas give rise to symptoms, thus many lesions are silent clinically). When patients are very concerned about MS we suggest more testing, ie adding an MRI of the cervical spine, SSEPs and lumbar punctures to obtain more evidence. The twitches that you describe have the characteristics of benign fasiculations and should not give rise to concern in the absence of weakness and atrophy of the muscles. Your EMG will help with this diagnosis as well.
I hope this has been helpful.
My response is not professional advice or meant to be taken as medical advice.
With that said: With the variables presented MS seems unlikely. The problem with numbness, as aforementioned, is a constant problem involving sleeping positions, tension, and the b.plexus. Other factors could be considered and clinical correlation is mandatory for deeper insight.
The twitches too are variable and non-specific. I am seeing more and more that unexplained benign neurological interuptions are commonly a result of stress (Neuropsychology) and sleep issues.
MS symptoms do not appear for a few hours and then go away but rather an attack, lasting weeks to months, and then relpase. Or to the contrary, for some, steady progression. If it has been several months since your last set of MRI/s and new and/or symptoms have become impressed. See a neurologist.
I hope that I have been helpful.
Good Luck!
JCmcc.
I too have had the same night numbness at times on and off in the past. I am still in limboland with no diagnosis.
I had what you describe twice badly - once in my left leg that lasted a couple of hours when I was in bed and the last time was my left arm, which is as you describe. This particular incident it took about 3-4 hours for it to subside completely. My alarm clock went off that morning, laying on my stomach and my alarm clock went off, went to turn it off with my right arm and did not realize my left arm was completely dead numb at which point I fell out of bed luckily not breaking anything.
I know this is a forum where some people will say it is not this, not that and some say MS does not cause these things, BUT everybody with MS or any other disease affecting the neurological system will have different symptoms and NOT all are the same. For example, the words "relapsing and remitting" means exactly that and "waxing and weaning".
It upsets me that when you, I or anybody are looking for answers, we get comments negating symptoms in which they should not.
My physician said it is the brain that is not firing the neurons to tell your body what to do etc.
You and only you know your own body, and are looking for a medical doctor's help on this forum as have I been. I know for myself that my severe night numbness IS NOT sleeping positions of the neck or spine, and particularly not psychological. IT IS REAL...
Just keep your head up and fight for the true answers your looking for......
terri
Please be aware that I am not responding to you as a physician and that my statements are conversational, educational, and are not to be taken as diagnosis, advice, or as professional.
With that said, let us take a look. I am also 28 and I know that it is horrid to deal with this in your youthful years.
There are many variables that I do not know. Your sex, your geographical location, pathology, et al. Therefore I am looking simply at what you told me.
As you may know there are a plethora of smaller, less common, or even larger conditions that can cause this sort of lateral neuritis that you are experiencing. The 30 day cycle would have made me suspicious of the sad condition of Multiple Sclerosis. However, with clear MRI studies of your brain and spine I am less likely to be suspicious. Your age factor as well would have made me suspicious of MS, in the clinical stats.
At this time you need to look deeper. I am not sure of your sexual history but something as rare as neurosyphilis could cause these problems as well as Amyotrophic Lateral Sclerosis (highly, highly unlikely). But, depending on your history I would not shy away from a deeper look at ticke born illnesses, such as Borreliosis also known as Lyme disease. This condition can present in odd ways and can attack your Central Nervous system in a very similar way to MS or ALS and can have no clinical findings. Whether or not it is Lyme disease will be found by your physician if he/she uses IGENEX labs in California and even then, if you do have it, maybe not at all.
Your symptoms are concerning and I am sorry that you are suffering. I cannot offer much more. I am constantly seeing people in your situation and most always they end up being missed/ignored cases of this controversial new condition: Lyme disease.
I hope that I have been helpful.
Good Luck!
JCmcc.
I want you to keep in mind that though your friends who have MS are frightened for you-this does not create facts. Often times, and unknown to them, folks who suffer with MS become wedded to their diagnosis and it becomes passionate. I am not saying this for them but it is a flag to keep an eye on.
If in four months you have lesions then the story becomes clearer, but, it does not rule out Lyme disease. Eastern US, makes it more probable for Lyme disease.
More than likely the test that you had was called the Elisa and physicians worth their weight will even tell you that the diagnosis of Lyme is clinical and that these tests are very unreliable.
Lyme disease lesions on the brain/sp. cord cannot be differentiated from those of MS and can cause the same sequences. I highly suggest that you do some serious research on the difficulty of diagnosing Lyme disease and its similarity to MS.
You may also be only watching the big symptoms-this is very common and, you may very well want to look at smaller things as apart of the map.
Good Luck!
JCmcc.
Hope this is helful,
JCmcc.
DEFINITIONS OF SYMPTOMS PERTAINING TO LYME DISEASE (General Symptoms)
Check clear circle
Translated into Lay English
**** *********
--I am not a physician and this is not meant to supplement your physicians assistance.
--No one person will have an identical experience with Lyme disease, no one patient will experience every symptom. All symptoms are non-specific for LD yet help to comprise a clinical and technical pathogenesis in which to present a clearer picture to your physician in as much that you receive the proper diagnoses.
o Nose Tingling
o Neck Stiffness
o Neck Pain
o Jaw Pain
o Jaw Stiffness
o Jaw Cramping
o Lock Jaw (Momentary/Chronic)
o Sore throat
o Clearing throat
o Phlegm (Chronic)
o Hoarseness
o Runny nose
o Ears (Decreased Hearing)
o Ears (Plugged)
o Ears (Buzzing)
o Ears (Pain)
o Ears (Sound Oversensitivity)
o Ears (Ringing)
o Ears (Popping)
o Eyes (Floaters)
o Eyes (Pain, In)
o Eyes (Pain, Around)
o Eyes (Pain, Behind)
o Eyes (Peripheral Waves)
o Eyes (Phantom Images)
o Eyes (Flashing lights)
o Eyes (Light Sensitivity)
o Vision (Blurred)
o Vision (Double)
o Vision (Loss)
o Hair Loss
o Shortness of Breath
o Speech (Thick)
o Speech (Slurred)
o Speech (Slow)
o Speech (Stammering)
o Dementia
o Diarrhea
o Constipation
o Difficulty Swallowing
o Drooling
o Short Term Memory Loss
o Long Term Memory Loss
o Clumsiness
o Headache
o Disorientation
o Loss of Sex Drive
o Sexual Dysfunction
o Bladder Dysfunction
o Bowel Dysfunction
o Fever (Recurring)
o Infections (Recurring)
o Low Temperature
o Migrating Pain
o Menstrual Pain/Irregular
o Breast Pain/Discharge
o Upset Stomach
o Nausea
o Bone pain
o Joint pain
o Stiffness (Joints)
o Stiffness (Extremities)
o Chest pain
o Muscle pain
o Spasms
o Cramps
o Night sweats
o Day sweats
o Unexplained Chills
o Heart Palpitations
o Fatigue
o Weakness (Limbs)
o Partial Paralysis (Limbs)
o Lymph Node Pain
o Lymph Node Swelling
o Dental Pain (Unexplained)
o Pain (generalized)
o Poor balance
o Increased Motion Sickness
o Lightheadedness
o Wooziness
o Heavy Headedness
o Insomnia
o Depression
o Irritability
o Mood swings
o Anxiety
o Weight Gain
o Weight Loss
o Testicular pain
o Pelvic pain
o Increased Alcohol Affect
o Worse hangover
o Allergy Sensitivity
o Chemical Sensitivity
o Unidentified skin blotches or freckles
SYMPTOMS REQUIRING CLEAR DEFINITION
(Other Symptoms)
(Definitions Below)
Circle black bullet
• Internal Vibration
• Pruritis
• Erythema Migrans
• Maculopapular Lesion/s
• Paresthesias
• Numbness
• Bell’s Palsy
• Vertigo
• Burning
• Heat Patches
• Stabbing Pain
• Shooting Pain
• Lhermitte’s Sign
• Short Term Memory Loss
• Long Term Memory Loss
• Head Pressure
• Lesions/Plaques (Brain)
• Lesions/Plaques (Spine)
• Twitching
• Fasculations
• Interstitial Cystitis
• Sphincter Dyssynergia
• Carpal Tunnel Syndrome
• GERD
• Malaise
• Gait
• Ataxia
• Sleep Apnea
• Atrophy
• Energy (Nocturnal)
• Spasticity
• Tremor
• Rigidity
• Bradykinesia
• Myoclonic Jerking
• Clonus
• Masking
• Micrographia
• Dysphagia
Summary Symptomatic Presentations can also occur:
• Choroiditis
• Conjunctivitis
• Endophthalmitis
• Keratitis
• Nystagmus
• Oculomotor (Weakness)
• Scleritis
• Uveitis
• Splenitis
Internal Vibration: -Term is self explanatory. Refers to a non-painful sensation within the internal body that can present it self anywhere within or have a mass internal effect. The sensation can be described as an internal vibration, flurry, rain storm, to name few. Symptom is non-specific.
Pruritus/ani: -Itching is a symptom we have all experienced but cannot easily describe or define. It is a peculiarly uncomfortable skin sensation. That much is certain. It may feel as if something is crawling on (or in) your skin. Itching can be diffuse (generalized) or localized -- all over or confined to a specific spot -- and there are many causes of diffuse and localized itching. Perhaps the best definition of itching is by the response it evokes -- it is a feeling that makes you want to scratch.
Erythema Migrans: - Noted as the “Bull’s Eye Rash” which is specific to Lyme disease. It appears like a Bull’s Eye and may or may not be at the site of the tick bite. Lest than 15% of people infected with this condition recall a rash. There are other non-specific rashes and skin lesions that are believed to have direct correlation to this etiology.
Maculopapular Lesion: -Noted in several cases, patient can have one to many. They appear dark red and are generally rectangular. They may or may not be associated with pruritis.
Paresthesias: -Abnormal nerve sensations such as pins-and-needles, tingling, burning, prickling or similar feelings are all known as "parethesias". They usually result from nerve damage due to pressure (such as a pinched nerve), entrapment, or diseases. Continued nerve damage can lead to numbness. Paresthesias can affect various parts of the body. Hands, fingers, and feet are common sites but all are possibilities. Afflictions of specific nerves or spinal nerves can also cause parethesias in particular skin areas of the body.
Numbness: -Deprived of the power to feel or move normally. A general loss of feeling or sensation that can be topical or complete. Can effect any part of the body.
Bell’s Palsy: -Partial facial paralysis from facial nerve damage. Bell's palsy is a form of facial paralysis resulting from damage to the 7th (facial) cranial nerve. A form of Bell’s Palsy can also happen in the stomach region.
Vertigo: -Feeling that the room or person is moving or spinning. The person can also experience sensations that indicate altitudinous changes, i.e. drops/climbs. Vertigo is the sensation that the room is moving or spinning, or that the person is moving or spinning within the environment. The term "dizziness" is often used for milder feelings of lightheadedness, but this word needs to be distinguished from symptoms such as balance difficulty, fainting, or general weakness. True dizziness is a lightheadedness or a sensation that you are about to faint. True vertigo requires the sensation of movement. Any dizziness or vertigo symptom needs prompt professional medical advice.
Burning: -Sensations that feel like burning in different parts of the body. It varies from mild and benign to extreme. It is a part of parethesias.
Heat patches: -A part of parethesias. A sensation of hot spots in different areas of the body.
Stabbing pain/Shooting pain: -A part of parethesias, self explanatory.
Lhermitte’s Sign: -Lhermitte's symptom is that of an electrical sensation in the spine or limbs on neck flexion. It can also cause buzzing patches throughout the limbs and or face.
Pressure in Head: -A sensation of “water on the brain” and pressure that is variable in affectation.
White Matter Lesions: -Plaques within the brain or spinal cord that are demyelinating. They are generally non-specific and have certain evidences that specify them more clearly. Such as ovoid lesions that are periventricular are most commonly seen in multiple sclerosis and Lyme disease.
Twitching/Fasciculations: -There are benign fasciculations that occur. Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations can often by visualized and take the form of a muscle twitch or dimpling under the skin, but usually do not generate sufficient force to move a limb. Twitching is listed as an alternate name or description for symptom Twitches. For a medical symptom description of 'Twitching', the following symptom information may be relevant to the symptoms: Twitches (symptom). However, note that other causes of the symptom 'Twitching' may be possible.
Interstitial cystitis: -Interstitial cystitis (IC), one of the chronic pelvic pain disorders, is a condition resulting in recurring discomfort or pain in the bladder and the surrounding pelvic region. Interstitial cystitis is an odd disease that is difficult to diagnose. It causes pain and irritation to the bladder and pelvic area, and thereby causes various urination symptoms. Its cause is unclear, but may be autoimmune, or perhaps only some cases are autoimmune. Diagnosis of IC is often by ruling out all other possible causes of bladder symptoms. Confirmation of a diagnosis is difficult, and the most compelling evidence for diagnosis is often from surgery and biopsy, rather than any specific urine or blood tests.
External Sphincter Dyssynergia (DESD): -The sphincter externalizes itself creating what appears to be a sensation of a small soft golf ball size addition around the anus.
Carpal tunnel syndrome: -Hand or wrist problems; often from repetitive motion. Carpal tunnel syndrome occurs when tendons or ligaments in the wrist become enlarged, often from inflammation, after being aggravated. The narrowed tunnel of bones and ligaments in the wrist pinches the nerves that reach the fingers and the muscles at the base of the thumb.
GERD: -Reflux refers to the stomach acid rising up the "wrong way" back up the esophagus and sometimes into the mouth. When this occurs chronically it is probably caused by Gastroesophageal Reflux Disease (GERD). Symptoms typically include recurrent heartburn, reflux, and regurgitation, but may also include chest pain, hoarseness or swallowing difficulty; see also other symptoms of GERD. Diagnosis of GERD requires consideration of other possible underlying conditions causing symptoms, such as hiatal hernia.
Malaise: -General feelings of discomfort or being ill-at-ease.
Gait: -Difficulty walking, such as Ataxia.
Ataxia: -Clumsiness, loss of balance, inability to walk a straight line.
Sleep Apnea: -Sleep apnea is a common disorder in which breathing stops during sleep for 10 seconds or more, sometimes more than 300 times a night. The hallmark of the disorder is excessive daytime sleepiness and compromised quality of life, including significant social and emotional problems.
Atrophy: -General name for any wasting away of muscles or body tissue.
Myoclonic Jerking: -One may be jerked or jolted awake by an unknown cause. Action myoclonus is characterized by muscular jerking triggered or intensified by voluntary movement or even the intention to move. It may be made worse by attempts at precise, coordinated movements. Action myoclonus is the most disabling form of myoclonus and can affect the arms, legs, face, and even the voice. This type of myoclonus often is caused by brain damage that results from a lack of oxygen and blood flow to the brain when breathing or heartbeat is temporarily stopped.
Clonus: -Clonus is repetitive, rhythmic contractions of a muscle when attempting to hold it in a stretched state. It is a strong, deep tendon reflex that occurs when the central nervous system fails to inhibit it. Clonus is not the same thing as myoclonus, which is irregular and uncontrollable jerks of a muscle or group of muscles (see above).
Expressed Energy Nocturnal: A sensation that one wants to run while trying to fall asleep. All of these symptoms may be present due to restless leg syndrome. Restless legs syndrome is a sensory-motor (movement) disorder characterized by uncomfortable sensations in the legs, which are worse during periods of inactivity or rest or while sitting or lying down. There is often a positive family history of the disorder.
Spasticity: -Spasticity is a condition in which certain muscles are continuously contracted. This contraction causes stiffness or tightness of the muscles and may interfere with gait, movement, and speech.
Tremor: -Tremor in the hand or foot on one side of the body, or less commonly in the jaw or face. It appears as a "beating" or oscillating movement. Because the tremor usually appears when a person's muscles are relaxed, it is called "resting tremor." This means that the affected body part trembles when it is not doing work, and it usually subsides when a person begins an action. The tremor often spreads to the other side of the body as the disease progresses, but remains most apparent on the original side of occurrence.
Rigidity: -Rigidity, also called increased muscle tone, means stiffness or inflexibility of the muscles. Muscles normally stretch when they move, and then relax when they are at rest. In rigidity, the muscle tone of an affected limb is always stiff and does not relax, sometimes resulting in a decreased range of motion. For example, a person who has rigidity may not be able to swing his or her arms when walking because the muscles are too tight. Rigidity can cause pain and cramping.
Bradykinesia: -Bradykinesia is the phenomenon of a person experiencing slow movements. In addition to slow movements, a person with bradykinesia will probably also have incomplete movement, difficulty initiating movements and sudden stopping of ongoing movement. People who have bradykinesia may walk with short, shuffling steps (this is called festination). Bradykinesia and rigidity can occur in the facial muscles, reducing a person's range of facial expressions and resulting in a "mask-like" appearance.
Postural instability or impaired balance and coordination: -An experience of instability when standing or impaired balance and coordination. These symptoms, combined with other symptoms such as bradykinesia, increase the probability of falling. People with balance problems may have difficulty making turns or abrupt movements. They may go through periods of "freezing," which is when a person feels stuck to the ground and finds it difficult to start walking. The slowness and incompleteness of movement can also affect speaking and swallowing.
Micrographia: - small, cramped handwriting.
Masking: -Loss of facial expression.
Dysphagia: -Difficulty or pain when swallowing.
Choroiditis: -Inflammation of the choroid in which the sensory retina becomes edematous and opaque. The inflammatory cells and exudate may burst through the sensory retina to cloud the vitreous body.
Endophthalmitis: - Suppurative inflammation of the tissues of the internal structures of the eye; not all layers of the uvea are affected. Fungi, necrosis of intraocular tumors, and retained intraocular foreign bodies often cause a purulent endophthalmitis.
Oculomotor (Weakness): -Nerve disruption in the oculomotor.
Uveitis: -Acute or chronic inflammation of the iris and ciliary body characterized by exudates into the anterior chamber, discoloration of the iris, and constricted, sluggish pupil. Symptoms include radiating pain, photophobia, lacrimation, and interference with vision.
Scleritis: -Inflammation of the white part of eyeball. Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.
Splenitis: -Inflammation of the spleen.
Nystagmus: - Involuntary jerky eye movements. The presence or absence of nystagmus is often used in the diagnosis of a variety of neurological and visual disorders. The list of signs and symptoms mentioned in various sources for Nystagmus includes those listed below. Note that Nystagmus symptoms usually refers to various symptoms known to a patient, but the phrase Nystagmus signs may refer to those signs only noticable by a doctor:
• Involuntary eye movements
• Eyes moving side to side - most common
• Eyes moving up and down
• Eyes moving in circles
• Both eyes moving together
Keratitis: - Inflammation of the cornea. The list of signs and symptoms mentioned in various sources for Keratitis includes those listed below. Note that Keratitis symptoms usually refers to various symptoms known to a patient, but the phrase Keratitis signs may refer to those signs only noticable by a doctor:
• Red eye
• Eye inflammation
• Watering eye
• Severe eye pain
• Blurred vision
• Yellow eye discharge
• Light sensitivity
Conjunctivitis: - The list of signs and symptoms mentioned in various sources for Conjunctivitis includes those listed below. Note that Conjunctivitis symptoms usually refers to various symptoms known to a patient, but the phrase Conjunctivitis signs may refer to those signs only noticable by a doctor:
• Pink eye
• Irritated eye
• Eye discharge
• Swollen eyelid
• Reddened eye
• Crusting eye
• Eyelids glued shut after sleep
• Eye pain
• Eye discomfort
• Gritty eye
• Itchy eye
• Yellow eye discharge
• Light sensitivity
End Notation.
As well, these symptoms present in more severe sequences and they have a direct pathogenesis.
In short, pretty much-NO.
Let me just say this....if you have been diagnosed with Lyme disease then you totally understand the symptom list.
Lesley
Each and every post as a clear disclaimer and not each and every post states Lyme disease, if, for example, you were to look into the archives.
Each post states that whether or not I am, say a resident or say a caring retired neurologist, states that I AM NOT RESPONDING AS A PHYSICIAN.
I am in completely compliance with the guidlines.
Not your concern.
Current treatment for Multiple Sclerosis is basically only to relieve symptoms and to hopefully lessen the attacks, but generally speaking it does not stop the disease process.
Lyme disease can mimic MS in every sigle way, including lesions. Therefore if someone has MS type symptoms then Lyme should be thoroughly investigated as a "possible" cause for the MS type presentation, especially when other causes have been ruled out. There are many many stories of people that have been treated for Lyme whose MS type symptoms were cured.
There are even some stories of MS that has been "cured" with the use of anti virals. My point being that perhaps some kind of pathogen is causing this disease, in some cases anyway. Full investigation into the possible causes of MS should take place, in my opinion anyway, but I would prefer to look for a cure to my maladies than just a diagnosis.
Shangs