Painful feet caused by neuropathy, no known cause

i have severe problems with my feet.  they are very painful to stand on for any length of time, i went to the cleveland cliic in florida 2 years ago and they found small nerve fibre neuropathy in ne of my feet, but found no cause.
a history of my porblems:6 years ago i started getting lower back "attacks"  which would come on very suddenlly, felt like a deep aching burning pain. At this time i also started to get pain in my legs (mostly at night when they were rested), which would feel like terrible growing pains, and made it very difficult to sleep.  My legs were so uncomfortable and restless. this progressed to a fibromyaligia like state, where my whole body felt sore most of the time. both day and night, i felt like a truck had run over me, and i was exhausted. two years ago i was standing up working when i felt this pain settle in the soles of both feet. i could not stand on them for more than five minutes at a time without feeling like my body weight was too much (i only weighed 130lbs and am 5'7"). when i got no help from the foot doctors, i went to the cleveland clinic, where they ran a vairiety of tests, diabetes, auto immune, and nerve conduction tests, mris, and the only thisg they saw was small nerve fibre neuropathy, but only a small amount in only one foot.  they prescribed zoloft, which did not work, and had mental side effects that were not tolerable.  i felt better for a brief time, while consuming a whole food diet eliminating grains and dairy. could my body be producing a toxic reaction to something? it's very scary not knowing the cause. any advice

[CCF-Neuro-M.D.-PW]

I cannot give you a clinical diagosis over the internet as this site is purely educational

In up to 30% of cases, small fiber neuropathy remains undiagnosed although new tests such as epidermal skin biopsy looking at epidermal nerve fiber abnormalities is increasing the diagostic yield. These tests are available at neuromuscular centers such as the Cleveland Clinic in Cleveland.

Another cause of restless and uncomfortable feelings in bed is restless legs syndrome, and this diagnosis should be considered by your doctors as there is effective treatment available. It is a clinical diagnosis based on history and response to treatment - medications such as dopamine agonists (pramipexole, ropinirole).

Good luck

[floxie]

Sorry about your foot problems.  I have had the same exact thing happen to me but I was lucky to make the connection between the levaquin (cipro, avelox, tequin etc.)that I took.  Did you take any antibiotics during this time?

[tkstar]

I had been on Zoloft and Famvir for a while but no atibitotics.  did yours cause permanant damage?

[jcverive]

For neuropathic pain, both Neurontin (gabapentin) and Lyrica (pregabalin) have shown to be very effective, especially for constant burning pain syndromes. I personally got no significant benefit from Neurontin, even at very high doses, but the Lyrica has been a tremendous help.  The side-effect profiles of both drugs are generally minor, so ask your ohysician about them.  You may also want to ask about Cymbalta, which operates in a similar manner to Zoloft.  Cymbalta often works where Zoloft and other selective serotonin reuptake inhibitors (SSRIs) fail, since it works on both serotonin and norepinepherine.

[jcverive]

For neuropathic pain, both Neurontin (gabapentin) and Lyrica (pregabalin) have shown to be very effective, especially for constant burning pain syndromes. I personally got no significant benefit from Neurontin, even at very high doses, but the Lyrica has been a tremendous help.  The side-effect profiles of both drugs are generally minor, so ask your ohysician about them.  You may also want to ask about Cymbalta, which operates in a similar manner to Zoloft.  Cymbalta often works where Zoloft and other selective serotonin reuptake inhibitors (SSRIs) fail, since it works on both serotonin and norepinepherine.

[tyler15_]

I have the same issues.

[stressed53]

A related discussion, Can PAD cause chronic feet pain? was started.