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Neurology  (Expert Forum)
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Paresthesia 9 months is this really neuropathy
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Paresthesia 9 months is this really neuropathy

by Jeane__0, Dec 19, 1998 12:00AM

  Dear CCF:
  Nine months ago while on the medication Levaquin I experienced Paresthesias that then intensified with acute burning pain to my entire body and bone pain. I wrote to the Federal Drug Administration and on their listing of reported adverse drug reactions the Paresthesia Cases all said ongoing therapy next to them.  Can you explain two things.  First, is a Paresthesias that is ongoing for 9 months with acute burning pain really
  small fiber neuropathy?  That is, is a Paresthesia and a Small Fiber Neuropathy the same thing. Second, would a Paresthesia last 9 months and include not only intense burning pain but bone and joint pain along with
  stiffness to the body.  Do Paresthesias cause stiffness to the body.
  Lastly does anyone know whether these type of adverse reactions resolve in time.
===================================================================
Thanks for your question.  The term "paresthesia" refers to a diminished
skin sensation such as numbness.  It is also used for sensations of "tingling",
"pins-and-needle", but usually not used for the description of pain.
Small Fiber Neuropathy (SFN) is one type of lesion of the small caliber,
unmyelinated nerve fibers that usually transmits the sensations of
temperature and pain.  SFN usually manifests as paresthesia, however the
two terms are not equivalent; for instance, a stroke can also cause
paresthesias.  It is possible, although not common, for a drug-reaction
type nerve damage to have lingering effects, but given your past experience
with other medications, your physician should definitely consider this
possibility.  SFN should NOT have any motor manifestations (e.g. stiffness).
Because of the occurrence of osteo-articular pain, your physician should
also consider the possibility of a more generalized inflammatory process,
and follow-up with some "Acute Phase" blood tests, such as Sedimentation
Rate, C-Reactive Protein level, CBC.
I hope this information is helpful.  Best of luck.
This information is provided for general medical education purposes only.
Please consult your doctor regarding diagnostic and treatment options.





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