Peripheral Neuropathy and Allopurinol

    
      Re: Peripheral Neuropathy and Allopurinol
    


[ Follow Ups ] [ Post Followup ] [ The Neurology Forum ] [ FAQ ]



Posted by CCF MD on September 25, 1997 at 10:55:51:

In Reply to: Peripheral Neuropathy and Allopurinol posted by Ted McMullen on September 19, 1997 at 11:39:08:

: I have PN which has progressed to the point where I have difficulty
  in walking. Extensive testing of all sorts has failed to locate a cause
  or source for this condition.
  I have also been taking Zyloprim (allopurinol) to prevent gout in rather
  large dosage (300 mg daily) for 20 or more years. The PDR shows that
  allopurinol can be the cause of PN in 15% on the population who use this
  drug, so I have discontinued it's use.
  If this was the cause of my condition, will the PN diminish in time,
  or possibly completely reverse itself?
  Thank
===========================================================================
The PDR lists allopurinol as having PN reported in less than 1% of cases. I asked
our neuromuscular people and they have not seen this as a cause so I can't
help you much in terms of the likelyhood that your PN will get better off the drug.
Many cases of PN go undiagnosed and you should speak with your neurologist specifically.
I have tried to call Glaxo Wellcome who make this medication but have been unable to
get through. The number listed in the PDR is 1800 334 0089. Good luck.
This information is provided for general medical education purposes only. Please consult
your physician for diagnostic and treatment options of your specific medical condition.