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Neurology (Expert Forum)
Possible Reaction to Dilantin and NSAIDS
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Possible Reaction to Dilantin and NSAIDS
by Yorkie2, Dec 29, 2003 12:00AM
I've been on 300 mg Dilantin and 81 mg aspirin for 14 months. (In July 2003 my Dilantin level was 31 - at that time I was also on BP meds - levels came down and Dilantin reduced to 300 mg from 400 mg and I was taken off the BP meds.) In August I had a bout with thrush in the mouth. Now I have developed mouth sores on cheek and under side of tongue. Dentist has ruled out problems with my teeth and feels I am having a reaction to Dilantin and some NSAIDS - Erythema Multiforme. He's going to prescribe a topical steriod with neurologist concurrence. Do I need to be concerned that there may be other health issues associated with this? Is it possible to have a reaction now after all this time? I had a ruptured brain aneurysm 10/17/2002 which was coiled. I had a second aneurysm coiled 5/8/2003. Other than topical corticosteriods prescribed by dermatologist I only take an occasional Tylenol or Benadryl. Thank you.
Doctor's Answer
by CCF-Neuro-M.D.-CS, Dec 31, 2003 12:00AM
It is true that Dilantin can cause skin reactions or cause disorders which could cause skin symptoms, but given the fact that you have been on it for a while without symptoms makes me pause. It still may be the Dilantin, but I would have other disorders such as connective tissue or inflammatory disorders evaluated. Also Dilantin can cause your white blood cells to decline which may predispose you to infections. This can be evaluated by having a complete blood count performed.
I assume you were placed on Dilantin for seizure prophylaxis. If you have not had a seizure then you may be able to come off the Dilantin. You can discuss this with you Neurologist. Good luck.
I assume you were placed on Dilantin for seizure prophylaxis. If you have not had a seizure then you may be able to come off the Dilantin. You can discuss this with you Neurologist. Good luck.
