Aa
A
A
Close
Avatar universal
Primary Lateral Sclerosis (PLS) & amyloidosis
My husband has been diagnosed with PLS (Primary Lateral Sclerosis) and amyloidosis.  Just this past week he has been treated with IgG to help slow the progress of these diseases.  Do you have any patients that are suffering from PLS & amyloidosis?  Are they taking any other type of treatments that help with these diseases.  Is their research that is being done regarding PLS and amyloidosis?  Any help is greatly appreciated.  Thank you.
Cancel
1 Answers
Page 1 of 1
Avatar universal
Hello sunshine2115
Treatment for individuals with PLS is symptomatic. Baclofen and tizanidine may reduce spasticity. Quinine or phenytoin may decrease cramps. Physical therapy often helps prevent joint immobility. Speech therapy may be useful for those with involvement of the facial muscles.
PLS is not fatal.  There is no cure, and the progression of symptoms varies.  Some people may retain the ability to walk without assistance, but others eventually require wheelchairs, canes, or other assistive devices
In amyloidosis treatment options depends on the type of amyloidosis and involves correcting organ failure .C ancer chemotherapy medication melphalan ,Alkeran,is being researched in conjunction with bone-marrow stem-cells transplantation. The results have been promising, and this combination treatment is offered to eradicate the amyloidosis in selected patients, provided that the underlying medical condition of the patient is adequate. These aggressive treatment options with stem-cell transplantation and high doses of chemotherapy are a true breakthrough in the treatment of these patients.
You should discuss regarding these options with your physician and hope for the best.

Reference http://www.ninds.nih.gov/disorders/primary_lateral_sclerosis/primary_lateral_sclerosis.htm
http://www.medicinenet.com/amyloidosis/page2.htm
Best
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Your Answer
Avatar universal
Answer
Know how to answer? Tap here to leave your answer...
Answer
Submit Answer
A
A
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Neurology Community Resources
Top Neurology Answerers
620923 tn?1452919248
Blank
selmaS
Allentown, PA
Avatar m tn
Blank
caregiver222
11079760 tn?1449081557
Blank
cjtmn
Minneapolis, MN
209987 tn?1451939065
Blank
tschock
AB
5265383 tn?1465260698
Blank
aspen2
ON
1780921 tn?1462244109
Blank
flipper336
Queen Creek, AZ