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Neurology (Expert Forum)
Re: cortical dysplasia
This forum is for questions and support regarding neurology issues such as: Alzheimer's Disease, ALS, Autism, Brain Cancer, Cerebral Palsy, Chronic Pain, Epilepsy, Fibromyalgia, Headaches, MS, Neuralgia, Neuropathy, Parkinson's Disease, RSD, Sleep Disorders, Stroke, Traumatic Brain Injury.
Re: cortical dysplasia
by CCF Neuro MD*, Jan 01, 1995 12:00AM
Posted By CCF Neuro MD* on November 08, 1998 at 13:12:06:
In Reply to: cortical dysplasia posted by Lucy De Palma on November 08, 1998 at 11:44:44:
My cousin's 15 month old baby has had the following diagnosis:
Spastic tetraparesis in a subject with cortical dysplasia
(pachygirya in fronto-parietal-temporal areas).
We have found it difficult to find much information about this disorder
and its treatment. We would appreciate some details about its severity
and any treatment available. Alternatively, could you let us know
where we could could find out more information.
Dear Lucy,
Pachygyria refers to a malformation of the brain that occurs during fetal development. The mechanism of injury is due to a failure of the normal germ cells to migrate. The result is an abnormal brain architecture with thick, flat folds. The process can occur in a specific region or involve the whole brain. From your description (frontal, parietal, and temporal region), the majority of the brain cortex is involved. Affected infants are frequently severely retarded and have delayed developmental milestones. The spastic tertaparesis refers to a weakness that is affecting all four extremities (arms/legs). There is no specific treatment other than supportive care. If the baby has not been evaluated, I recommend getting an appointment with a pediatric neurologist. The doctor may be able to give you additional information or refer you to a local medical library etc. If you are interested in getting an appointment at CCF, call 1-800-CCF-CARE. Good Luck.
In Reply to: cortical dysplasia posted by Lucy De Palma on November 08, 1998 at 11:44:44:
My cousin's 15 month old baby has had the following diagnosis:
Spastic tetraparesis in a subject with cortical dysplasia
(pachygirya in fronto-parietal-temporal areas).
We have found it difficult to find much information about this disorder
and its treatment. We would appreciate some details about its severity
and any treatment available. Alternatively, could you let us know
where we could could find out more information.
Dear Lucy,
Pachygyria refers to a malformation of the brain that occurs during fetal development. The mechanism of injury is due to a failure of the normal germ cells to migrate. The result is an abnormal brain architecture with thick, flat folds. The process can occur in a specific region or involve the whole brain. From your description (frontal, parietal, and temporal region), the majority of the brain cortex is involved. Affected infants are frequently severely retarded and have delayed developmental milestones. The spastic tertaparesis refers to a weakness that is affecting all four extremities (arms/legs). There is no specific treatment other than supportive care. If the baby has not been evaluated, I recommend getting an appointment with a pediatric neurologist. The doctor may be able to give you additional information or refer you to a local medical library etc. If you are interested in getting an appointment at CCF, call 1-800-CCF-CARE. Good Luck.
