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Neurology  (Expert Forum)
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Sciatic nerve damaged from radiation
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Sciatic nerve damaged from radiation

by Femi, Oct 13, 2005 12:00AM
My partner had a big tumor removed from his thigh in 2001 and got radiation before and during the operation.  Half a year later problems started in his lower legs: numbness, tingling, pain and weakness - often not being able to walk more than 200 metres. The neurologist diagnosed a damage of the sciatic nerve in the area where the operation was, very probably due to radiation (EMG: sciatic neuropathy).
It got slightly worse with the years and pain is occurring especially after exercise, often a swelling at the ankle increases the problem.
Findings of neurologist (attempt to translate from German):
Missing ASR, Toelifting-parese, not possible to walk on toes or heel, no restriction in knee area, Tinel`sches signal along backside of thigh (where scar – about 1 ft long) and beyond knee, Hypalgesie in lower leg not including inner side
Judgement:
Peripher damage of sciadic nerve, comprising Peronaeus-area, and also Tibialis-area,
Obviously no formation of a Neurom (according to MRI-pictures)

No doctor can do anything for my partner here in Germany where we live. (He is an American citizen.)
Any advice? Thank You very much.

by CCF-Neuro-M.D.-PW, Oct 20, 2005 12:00AM
Unfortunetely one of the side effects of radiation is damage to nerves, which is typically seen in a delayed fashion as you describe. There is no current treatment to reverse or regrow the nerve that is damaged. Nerves can regrow to a certain extent over months, but scar tissue from the readiation will likely prevent this (if abnormally regrown a painful 'neuroma' or ball of nerve tissue can form). After 12 months, maximum regrowth is seen, and any function not recovered will likelynot get better. I do not know your husbands case in detail, so whetherthings liketendon transfer surgery or rehabilitation prosthesis may help, I do not know. Thefocus at this point though should be rehabilitation

Good luck
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