Spinal Spasms and MG

Can spine spasms/hardening and tightened back muscles be related to MG? I was undiagnosed for years and once I was put on Mestinon, my back loosened, my headache went away, and my spine pain/brittleness went away for about 6 months. The Mestinon was not being as effective, and my back problems were returning. My neurologist put me on Cellcept and 40 mg prednisone.  After being on the prednisone for 2 weeks, my symptoms started getting better (less spine pain, eye stayed open longer, not as much blurry vision). Now that I have been up to the 2000mg Cellcept daily for awhile, she is weaning me off the prednisone. My spine is getting very tight and yet brittle again and my back muscles are tightening (especially through the shoulder/rib area). She believes the spine issues are unrelated, yet it got so much better in the beginning that I didn't even know you could feel that good! I have had MRI's of cervical and thoracic spine. I do have some bulging and herniation of which I have had numerous physical therapy sessions and a injection into thoracic spine.  Any advice would be much appreciated.
Thanks!

[DrNavneetMD]

Hello Dear,

Cellcept is a steroid-sparing agent and can be used in combination immunotherapy in severe /refractory cases.In short term cellcept would add benefit but discus the long term complications and adverse effects of cellcept.
Mestinon is an orally active cholinesterase inhibitor which prevents the breakdown of acetylcholine by allowing more acetylcholine to accumulate. Hence, helps in the better control of the voluntary muscle function. You can discuss the option of restarting mestinon again as an add on therapy.

Best
Take care